FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029112298> ?p ?o ?g. }

• W2029112298 endingPage "892" @default.
• W2029112298 startingPage "880" @default.
• W2029112298 abstract "We combine comparative genomic measures and the distance separating adjacent genes to predict operons in 124 completely sequenced prokaryotic genomes. Our method automatically tailors itself to each genome using sequence information alone, and thus can be applied to any prokaryote. For Escherichia coli K12 and Bacillus subtilis, our method is 85 and 83% accurate, respectively, which is similar to the accuracy of methods that use the same features but are trained on experimentally characterized transcripts. In Halobacterium NRC-1 and in Helicobacter pylori, our method correctly infers that genes in operons are separated by shorter distances than they are in E.coli, and its predictions using distance alone are more accurate than distance-only predictions trained on a database of E.coli transcripts. We use microarray data from six phylogenetically diverse prokaryotes to show that combining intergenic distance with comparative genomic measures further improves accuracy and that our method is broadly effective. Finally, we survey operon structure across 124 genomes, and find several surprises: H.pylori has many operons, contrary to previous reports; Bacillus anthracis has an unusual number of pseudogenes within conserved operons; and Synechocystis PCC 6803 has many operons even though it has unusually wide spacings between conserved adjacent genes." @default.
• W2029112298 created "2016-06-24" @default.
• W2029112298 creator A5066623854 @default.
• W2029112298 creator A5072368469 @default.
• W2029112298 creator A5090691804 @default.
• W2029112298 creator A5091119492 @default.
• W2029112298 date "2005-02-18" @default.
• W2029112298 modified "2023-09-30" @default.
• W2029112298 title "A novel method for accurate operon predictions in all sequenced prokaryotes" @default.
• W2029112298 cites W1947762817 @default.
• W2029112298 cites W1972314084 @default.
• W2029112298 cites W1995117714 @default.
• W2029112298 cites W2025853251 @default.
• W2029112298 cites W2039700732 @default.
• W2029112298 cites W2053150867 @default.
• W2029112298 cites W2058588742 @default.
• W2029112298 cites W2061732951 @default.
• W2029112298 cites W2062402656 @default.
• W2029112298 cites W2083788527 @default.
• W2029112298 cites W2100332892 @default.
• W2029112298 cites W2102498314 @default.
• W2029112298 cites W2105792118 @default.
• W2029112298 cites W2106913956 @default.
• W2029112298 cites W2107717979 @default.
• W2029112298 cites W2109621905 @default.
• W2029112298 cites W2117190895 @default.
• W2029112298 cites W2120904752 @default.
• W2029112298 cites W2122665495 @default.
• W2029112298 cites W2126161931 @default.
• W2029112298 cites W2127596034 @default.
• W2029112298 cites W2133312664 @default.
• W2029112298 cites W2152812151 @default.
• W2029112298 cites W2157865313 @default.
• W2029112298 cites W2159656294 @default.
• W2029112298 cites W2160453515 @default.
• W2029112298 cites W2166330697 @default.
• W2029112298 cites W2168786813 @default.
• W2029112298 cites W2169929748 @default.
• W2029112298 cites W2328176404 @default.
• W2029112298 cites W4252706339 @default.
• W2029112298 doi "https://doi.org/10.1093/nar/gki232" @default.
• W2029112298 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/549399" @default.
• W2029112298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15701760" @default.
• W2029112298 hasPublicationYear "2005" @default.
• W2029112298 type Work @default.
• W2029112298 sameAs 2029112298 @default.
• W2029112298 citedByCount "339" @default.
• W2029112298 countsByYear W20291122982012 @default.
• W2029112298 countsByYear W20291122982013 @default.
• W2029112298 countsByYear W20291122982014 @default.
• W2029112298 countsByYear W20291122982015 @default.
• W2029112298 countsByYear W20291122982016 @default.
• W2029112298 countsByYear W20291122982017 @default.
• W2029112298 countsByYear W20291122982018 @default.
• W2029112298 countsByYear W20291122982019 @default.
• W2029112298 countsByYear W20291122982020 @default.
• W2029112298 countsByYear W20291122982021 @default.
• W2029112298 countsByYear W20291122982022 @default.
• W2029112298 countsByYear W20291122982023 @default.
• W2029112298 crossrefType "journal-article" @default.
• W2029112298 hasAuthorship W2029112298A5066623854 @default.
• W2029112298 hasAuthorship W2029112298A5072368469 @default.
• W2029112298 hasAuthorship W2029112298A5090691804 @default.
• W2029112298 hasAuthorship W2029112298A5091119492 @default.
• W2029112298 hasBestOaLocation W20291122981 @default.
• W2029112298 hasConcept C104317684 @default.
• W2029112298 hasConcept C141231307 @default.
• W2029112298 hasConcept C195139083 @default.
• W2029112298 hasConcept C203075996 @default.
• W2029112298 hasConcept C2777272437 @default.
• W2029112298 hasConcept C2780918051 @default.
• W2029112298 hasConcept C34957205 @default.
• W2029112298 hasConcept C3742359 @default.
• W2029112298 hasConcept C523546767 @default.
• W2029112298 hasConcept C54355233 @default.
• W2029112298 hasConcept C547475151 @default.
• W2029112298 hasConcept C70721500 @default.
• W2029112298 hasConcept C86803240 @default.
• W2029112298 hasConceptScore W2029112298C104317684 @default.
• W2029112298 hasConceptScore W2029112298C141231307 @default.
• W2029112298 hasConceptScore W2029112298C195139083 @default.
• W2029112298 hasConceptScore W2029112298C203075996 @default.
• W2029112298 hasConceptScore W2029112298C2777272437 @default.
• W2029112298 hasConceptScore W2029112298C2780918051 @default.
• W2029112298 hasConceptScore W2029112298C34957205 @default.
• W2029112298 hasConceptScore W2029112298C3742359 @default.
• W2029112298 hasConceptScore W2029112298C523546767 @default.
• W2029112298 hasConceptScore W2029112298C54355233 @default.
• W2029112298 hasConceptScore W2029112298C547475151 @default.
• W2029112298 hasConceptScore W2029112298C70721500 @default.
• W2029112298 hasConceptScore W2029112298C86803240 @default.
• W2029112298 hasIssue "3" @default.
• W2029112298 hasLocation W20291122981 @default.
• W2029112298 hasLocation W20291122982 @default.
• W2029112298 hasLocation W20291122983 @default.
• W2029112298 hasLocation W20291122984 @default.
• W2029112298 hasLocation W20291122985 @default.
• W2029112298 hasLocation W20291122986 @default.

• next