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- W2029126350 abstract "Familial thrombocytosis is an extremely rare disorder, so far reported in only a handful of families. In the majority of cases the characteristics were of essential thrombocythemia. Most patients presented with a platelet count above 800,000/mm3, were diagnosed as having a myeloproliferative disease, and some required chemotherapy. We describe a benign form of familial thrombocytosis with autosomal dominant inheritance in five healthy members of three generations of a family, all of whom had moderate thrombocytosis within the range 422,000-662,000/mm3, characterized by low mean platelet volume. A careful medical history and a 5-year follow up of the subjects did not reveal any untoward clinical development. This variant of familial thrombocytosis is therefore of a benign nature. Possible mechanisms linking thrombocytosis with platelet microcytosis in this family are discussed." @default.
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- W2029126350 date "2008-06-28" @default.
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- W2029126350 title "Benign familial microcytic thrombocytosis with autosomal dominant transmission" @default.
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- W2029126350 doi "https://doi.org/10.1111/j.1399-0004.1997.tb02513.x" @default.
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