FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029142208> ?p ?o ?g. }

• W2029142208 endingPage "910" @default.
• W2029142208 startingPage "900" @default.
• W2029142208 abstract "It is well known that withdrawal of progesterone from the maternal circulation is a critical stimulus to parturition in rodents, such as rats and mice. However, mechanisms that determine the timing of progesterone withdrawal are not completely understood. In the present study, we examined whether the vascular endothelial growth factor (VEGF) system in the corpus luteum (CL) contributes to the regulation of circulating progesterone levels and acts as a determinant of the timing of parturition in mice. We found that reduction in the expression levels of VEGF and VEGF receptor-2 in the CL precedes the impairment of luteal circulation and a series of events leading to parturition (i.e., reduction of plasma progesterone, enhancement of myometrium contractility, and onset of parturition). Blocking of VEGF signaling by using the inhibitor of VEGFR tyrosine kinase KRN633 at mid-pregnancy caused a similar sequence of events and induced preterm birth. These results suggest that the VEGF system in the CL plays a critical role in maintaining a high level of circulating progesterone, and determining the timing of parturition in mice." @default.
• W2029142208 created "2016-06-24" @default.
• W2029142208 creator A5002232007 @default.
• W2029142208 creator A5045277847 @default.
• W2029142208 creator A5046333085 @default.
• W2029142208 creator A5047311681 @default.
• W2029142208 creator A5047776985 @default.
• W2029142208 creator A5075666358 @default.
• W2029142208 creator A5083010989 @default.
• W2029142208 creator A5083594474 @default.
• W2029142208 date "2013-01-10" @default.
• W2029142208 modified "2023-10-06" @default.
• W2029142208 title "Role of Vascular Endothelial Growth Factor in Maintenance of Pregnancy in Mice" @default.
• W2029142208 cites W1569470783 @default.
• W2029142208 cites W1679229092 @default.
• W2029142208 cites W1948205405 @default.
• W2029142208 cites W1971222830 @default.
• W2029142208 cites W1984998073 @default.
• W2029142208 cites W1991850739 @default.
• W2029142208 cites W2002292824 @default.
• W2029142208 cites W2006996083 @default.
• W2029142208 cites W2028031291 @default.
• W2029142208 cites W2033042065 @default.
• W2029142208 cites W2036751011 @default.
• W2029142208 cites W2036909895 @default.
• W2029142208 cites W2051057430 @default.
• W2029142208 cites W2065614074 @default.
• W2029142208 cites W2069929255 @default.
• W2029142208 cites W2073212944 @default.
• W2029142208 cites W2073666965 @default.
• W2029142208 cites W2085143898 @default.
• W2029142208 cites W2087403188 @default.
• W2029142208 cites W2088704507 @default.
• W2029142208 cites W2097069565 @default.
• W2029142208 cites W2105325611 @default.
• W2029142208 cites W2112885348 @default.
• W2029142208 cites W2115515762 @default.
• W2029142208 cites W2130098479 @default.
• W2029142208 cites W2132272301 @default.
• W2029142208 cites W2132509384 @default.
• W2029142208 cites W2141634517 @default.
• W2029142208 cites W2142980049 @default.
• W2029142208 cites W2148768012 @default.
• W2029142208 cites W2150214114 @default.
• W2029142208 cites W2157709564 @default.
• W2029142208 cites W2160056506 @default.
• W2029142208 cites W2161352629 @default.
• W2029142208 cites W2163545710 @default.
• W2029142208 cites W2171085327 @default.
• W2029142208 cites W48365001 @default.
• W2029142208 doi "https://doi.org/10.1210/en.2012-1967" @default.
• W2029142208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23307787" @default.
• W2029142208 hasPublicationYear "2013" @default.
• W2029142208 type Work @default.
• W2029142208 sameAs 2029142208 @default.
• W2029142208 citedByCount "17" @default.
• W2029142208 countsByYear W20291422082013 @default.
• W2029142208 countsByYear W20291422082014 @default.
• W2029142208 countsByYear W20291422082015 @default.
• W2029142208 countsByYear W20291422082017 @default.
• W2029142208 countsByYear W20291422082019 @default.
• W2029142208 countsByYear W20291422082020 @default.
• W2029142208 countsByYear W20291422082021 @default.
• W2029142208 countsByYear W20291422082022 @default.
• W2029142208 countsByYear W20291422082023 @default.
• W2029142208 crossrefType "journal-article" @default.
• W2029142208 hasAuthorship W2029142208A5002232007 @default.
• W2029142208 hasAuthorship W2029142208A5045277847 @default.
• W2029142208 hasAuthorship W2029142208A5046333085 @default.
• W2029142208 hasAuthorship W2029142208A5047311681 @default.
• W2029142208 hasAuthorship W2029142208A5047776985 @default.
• W2029142208 hasAuthorship W2029142208A5075666358 @default.
• W2029142208 hasAuthorship W2029142208A5083010989 @default.
• W2029142208 hasAuthorship W2029142208A5083594474 @default.
• W2029142208 hasBestOaLocation W20291422081 @default.
• W2029142208 hasConcept C126322002 @default.
• W2029142208 hasConcept C134018914 @default.
• W2029142208 hasConcept C143228043 @default.
• W2029142208 hasConcept C146285616 @default.
• W2029142208 hasConcept C14858245 @default.
• W2029142208 hasConcept C167734588 @default.
• W2029142208 hasConcept C170493617 @default.
• W2029142208 hasConcept C2776608385 @default.
• W2029142208 hasConcept C2777025900 @default.
• W2029142208 hasConcept C2778164554 @default.
• W2029142208 hasConcept C2779066055 @default.
• W2029142208 hasConcept C39133596 @default.
• W2029142208 hasConcept C71315377 @default.
• W2029142208 hasConcept C71924100 @default.
• W2029142208 hasConcept C86803240 @default.
• W2029142208 hasConceptScore W2029142208C126322002 @default.
• W2029142208 hasConceptScore W2029142208C134018914 @default.
• W2029142208 hasConceptScore W2029142208C143228043 @default.
• W2029142208 hasConceptScore W2029142208C146285616 @default.
• W2029142208 hasConceptScore W2029142208C14858245 @default.
• W2029142208 hasConceptScore W2029142208C167734588 @default.
• W2029142208 hasConceptScore W2029142208C170493617 @default.
• W2029142208 hasConceptScore W2029142208C2776608385 @default.

• next