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- W2029162846 abstract "Abstract The effect of hypotonic and hypertonic solutions on metabolism, functional activity, and ultrastructure of platelets was investigated as regards preservation by means of liquid nitrogen. In hypotonic plasma or in WARBURG-buffer/H 2 O-mixtures, metabolism, adhesion, and spreading of human platelets were less affected than by hypertonic solutions of NaCl in plasma or in WARBURG-buffer containing the 2- to 16-fold concentrations of Na + and K + . In solutions having an osmolarity of about 0.15 to 0.6 no irreversible damage of the platelets is evident concerning metabolism and functional activity. By very strong hypotonic and hypertonic solutions similar changes in platelet ultrastructure occur, including swelling and depletion of the various granules." @default.
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- W2029162846 date "1975-12-01" @default.
- W2029162846 modified "2023-09-27" @default.
- W2029162846 title "Investigations on the preservation of human platelets II. The influence of hypotonic and hypertonic solutions on metabolism, functions, and ultrastructure of platelets" @default.
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- W2029162846 doi "https://doi.org/10.1016/0049-3848(75)90093-6" @default.
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