FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029168122> ?p ?o ?g. }

• W2029168122 abstract "Cerebral palsy (CP) results from a static brain lesion during pregnancy or early life and remains the most common cause of physical disability in children (1 in 500). While the brain lesion is static, the physical manifestations and medical issues may progress resulting in altered motor patterns. To date, there are no prospective longitudinal studies of CP that follow a birth cohort to track early gross and fine motor development and use Magnetic Resonance Imaging (MRI) to determine the anatomical pattern and likely timing of the brain lesion. Existing studies do not consider treatment costs and outcomes. This study aims to determine the pathway(s) to motor outcome from diagnosis at 18 months corrected age (c.a.) to outcome at 5 years in relation to the nature of the brain lesion (using structural MRI). This prospective cohort study aims to recruit a total of 240 children diagnosed with CP born in Victoria (birth years 2004 and 2005) and Queensland (birth years 2006–2009). Children can enter the study at any time between 18 months to 5 years of age and will be assessed at 18, 24, 30, 36, 48 and 60 months c.a. Outcomes include gross motor function (GMFM-66 & GMFM-88), Gross Motor Function Classification System (GMFCS); musculoskeletal development (hip displacement, spasticity, muscle contracture), upper limb function (Manual Ability Classification System), communication difficulties using Communication and Symbolic Behaviour Scales-Developmental Profile (CSBS-DP), participation using the Paediatric Evaluation of Disability Inventory (PEDI), parent reported quality of life and classification of medical and allied health resource use and determination of the aetiology of CP using clinical evaluation combined with MRI. The relationship between the pathways to motor outcome and the nature of the brain lesion will be analysed using multiple methods including non-linear modelling, multilevel mixed-effects models and generalised estimating equations. This protocol describes a large population-based study of early motor development and brain structure in a representative sample of preschool aged children with CP, using direct clinical assessment. The results of this study will be published in peer reviewed journals and presented at relevant international conferences. Australia and New Zealand Clinical Trials Register ( ACTRN1261200169820 )" @default.
• W2029168122 created "2016-06-24" @default.
• W2029168122 creator A5001428499 @default.
• W2029168122 creator A5008735550 @default.
• W2029168122 creator A5013570044 @default.
• W2029168122 creator A5025122765 @default.
• W2029168122 creator A5027380083 @default.
• W2029168122 creator A5031707355 @default.
• W2029168122 creator A5033582075 @default.
• W2029168122 creator A5033683374 @default.
• W2029168122 creator A5041409126 @default.
• W2029168122 creator A5046872827 @default.
• W2029168122 creator A5052379108 @default.
• W2029168122 creator A5054441280 @default.
• W2029168122 creator A5055407749 @default.
• W2029168122 creator A5060978364 @default.
• W2029168122 creator A5063711471 @default.
• W2029168122 creator A5080275412 @default.
• W2029168122 creator A5084134799 @default.
• W2029168122 creator A5085502234 @default.
• W2029168122 date "2013-06-11" @default.
• W2029168122 modified "2023-10-12" @default.
• W2029168122 title "Australian Cerebral Palsy Child Study: protocol of a prospective population based study of motor and brain development of preschool aged children with cerebral palsy" @default.
• W2029168122 cites W1579046799 @default.
• W2029168122 cites W1589750505 @default.
• W2029168122 cites W1617154394 @default.
• W2029168122 cites W164262269 @default.
• W2029168122 cites W180102836 @default.
• W2029168122 cites W1942051723 @default.
• W2029168122 cites W1963745909 @default.
• W2029168122 cites W1967565859 @default.
• W2029168122 cites W1972718490 @default.
• W2029168122 cites W1972754165 @default.
• W2029168122 cites W1975049119 @default.
• W2029168122 cites W1976305068 @default.
• W2029168122 cites W1977786727 @default.
• W2029168122 cites W1979683501 @default.
• W2029168122 cites W1987213414 @default.
• W2029168122 cites W2010989450 @default.
• W2029168122 cites W2011481459 @default.
• W2029168122 cites W2018916507 @default.
• W2029168122 cites W2022167001 @default.
• W2029168122 cites W2028360958 @default.
• W2029168122 cites W2029260543 @default.
• W2029168122 cites W2032065370 @default.
• W2029168122 cites W2032113584 @default.
• W2029168122 cites W2033619039 @default.
• W2029168122 cites W2035516360 @default.
• W2029168122 cites W2037228807 @default.
• W2029168122 cites W2040872218 @default.
• W2029168122 cites W2042533161 @default.
• W2029168122 cites W2047158684 @default.
• W2029168122 cites W2048213914 @default.
• W2029168122 cites W2049615209 @default.
• W2029168122 cites W2050195411 @default.
• W2029168122 cites W2050351220 @default.
• W2029168122 cites W2056408510 @default.
• W2029168122 cites W2064544279 @default.
• W2029168122 cites W2072351348 @default.
• W2029168122 cites W2074790959 @default.
• W2029168122 cites W2077662287 @default.
• W2029168122 cites W2082126167 @default.
• W2029168122 cites W2085526001 @default.
• W2029168122 cites W2087969944 @default.
• W2029168122 cites W2108945230 @default.
• W2029168122 cites W2112015077 @default.
• W2029168122 cites W2112287353 @default.
• W2029168122 cites W2112624928 @default.
• W2029168122 cites W2121837619 @default.
• W2029168122 cites W2130221519 @default.
• W2029168122 cites W2133279598 @default.
• W2029168122 cites W2136593666 @default.
• W2029168122 cites W2136940458 @default.
• W2029168122 cites W2137007804 @default.
• W2029168122 cites W2141088707 @default.
• W2029168122 cites W2142373617 @default.
• W2029168122 cites W2142804751 @default.
• W2029168122 cites W2149860264 @default.
• W2029168122 cites W2153132838 @default.
• W2029168122 cites W2165016807 @default.
• W2029168122 cites W2168294280 @default.
• W2029168122 cites W2235688437 @default.
• W2029168122 cites W2270664102 @default.
• W2029168122 cites W2318845445 @default.
• W2029168122 cites W2331252326 @default.
• W2029168122 cites W2334104583 @default.
• W2029168122 cites W4245602911 @default.
• W2029168122 cites W4247162214 @default.
• W2029168122 cites W4253595818 @default.
• W2029168122 cites W50181633 @default.
• W2029168122 doi "https://doi.org/10.1186/1471-2377-13-57" @default.
• W2029168122 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3686628" @default.
• W2029168122 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23758951" @default.
• W2029168122 hasPublicationYear "2013" @default.
• W2029168122 type Work @default.
• W2029168122 sameAs 2029168122 @default.
• W2029168122 citedByCount "66" @default.
• W2029168122 countsByYear W20291681222013 @default.
• W2029168122 countsByYear W20291681222014 @default.
• W2029168122 countsByYear W20291681222015 @default.

• next