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- W2029191350 abstract "To the Editor.— In the article by Nalbandian and co-workers entitled Test for Hemoglobin S: A Critique ( 218 :1679-1680, 1971), it is stated that false-positive results may be given by non-S sickling such as C Harlem ... and hemoglobins. Some readers may interpret this statement to mean that the Heinz-body-forming hemoglobins both sickle and give positive Sickledex tests. To ascertain whether this is correct, we have examined blood specimens from four patients with unstable hemoglobin disorders: one patient with hemoglobin H disease, two with hemoglobin Koln disease (α 2 β 2 98 valine ), and one with hemoglobin Olmsted disease (α 2 β 2 141 arginine ). Sickle cell tests with 2% sodium metabisulfite were negative in each case. The saponin-dithionite turbidity test as specified by Nalbandian et al gave normal results in the patient with hemoglobin H disease and in both patients with hemoglobin Koln disease; however, the test" @default.
- W2029191350 created "2016-06-24" @default.
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- W2029191350 date "1972-04-03" @default.
- W2029191350 modified "2023-10-17" @default.
- W2029191350 title "Sickledex Tests With Unstable Hemoglobin Disorders" @default.
- W2029191350 doi "https://doi.org/10.1001/jama.1972.03200010112034" @default.
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- W2029191350 hasPublicationYear "1972" @default.
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