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- W2029203435 abstract "Thirty-six patients with Raynaud's disease (RD) were treated with a low dosage of β-blockers, atenolol (50 mg/day) or propranolol (20 mg/day). Previous data have suggested that the pathophysiology of RD may be mediated by presynaptic β-adrenoceptors. In this research we report that chronic β-blocker treatment, at low dosage, can prevent the cold-induced vasospasm. The majority of patients (28) responded to atenolol, and 8 patients refractory to atenolol responded to propranolol." @default.
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- W2029203435 date "1987-03-01" @default.
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- W2029203435 title "β-Blockers: A new therapeutic approach to Raynaud's disease" @default.
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- W2029203435 doi "https://doi.org/10.1016/0026-2862(87)90023-9" @default.
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