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- W2029226934 abstract "A new method for measuring coagulation in an extracorporeal circuit was developed for biocompatibility tests of 2 hemodialysis blood pumps (roller and Allient™ ventricle pump). Bovine blood was collected in citrate-anticoagulated 450mL blood bags. Heparin was added at 0.5 U/mL and CaCl2 was added to obtain ionized Ca level of 2 mEq/L. Blood was pumped through a blood transfusion filter (Pall Biomedical SQ40S, 40 μ) at ∼300 mL/min and returned to the bag. Pressure on both sides of the filter and the blood flow rate were continuously measured. Hydraulic resistance (HR) of anticoagulated blood is essentially stable. As blood starts to coagulate anywhere in the circuit, slope of HR increases at least 14-fold, usually much more. The tests demonstrated that coagulation properties are similar for the two pumps and that neither has high propensity for coagulation. This test method uses readily available sensors, is sensitive to small amounts of thrombus formation, and detects the onset of coagulation.Figure" @default.
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- W2029226934 date "2005-03-01" @default.
- W2029226934 modified "2023-10-14" @default.
- W2029226934 title "COAGULATION TEST METHOD FOR EXTRACORPOREAL BLOOD CIRCUITS" @default.
- W2029226934 doi "https://doi.org/10.1097/00002480-200503000-00173" @default.
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