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- W2029240033 abstract "Background Vaccination is often cited as a potential cause of immune‐mediated thrombocytopenia ( ITP ) in dogs. Although an association has been documented in humans, particularly in children, this relationship has not been definitively established in dogs. Objectives To identify the presence of an association between recent vaccination and ITP in dogs. Animals Forty‐eight client‐owned dogs with presumptive idiopathic ITP and 96 age‐matched, client‐owned dogs with non‐immune‐mediated disease. Methods Retrospective, case‐control study. Dogs were identified through the V eterinary M edical D atabase ( VMDB ) and H ospital I nformation S ystem at P urdue U niversity. Results The median age at presentation for dogs with ITP was 7 years (range: 2–15 years). The majority of the ITP group was comprised of mixed breed dogs (38%); no pure breed was represented by more than 3 cases. The number of dogs that were vaccinated within 42 days of diagnosis of ITP did not differ significantly ( P = .361) between cases of presumptive ITP (4/48, 8%) and the control group (13/96, 14%). Conclusions and Clinical Importance This study failed to confirm the presence of an association between presumptive idiopathic ITP in dogs and recent vaccination; however, the possibility of an association cannot be completely ruled out based on the small sample populations and requires further investigation." @default.
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- W2029240033 date "2011-12-13" @default.
- W2029240033 modified "2023-10-11" @default.
- W2029240033 title "Idiopathic Immune-Mediated Thrombocytopenia and Recent Vaccination in Dogs" @default.
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- W2029240033 doi "https://doi.org/10.1111/j.1939-1676.2011.00850.x" @default.
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