FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029249531> ?p ?o ?g. }

• W2029249531 abstract "The complete proteome of the starlet sea anemone, Nematostella vectensis, provides insights into gene invention dating back to the Cnidarian-Bilaterian ancestor. With the addition of the complete proteomes of Hydra magnipapillata and Monosiga brevicollis, the investigation of proteins having unique features in early metazoan life has become practical. We focused on the properties and the evolutionary trends of tandem repeat (TR) sequences in Cnidaria proteomes.We found that 11-16% of N. vectensis proteins contain tandem repeats. Most TRs cover 150 amino acid segments that are comprised of basic units of 5-20 amino acids. In total, the N. Vectensis proteome has about 3300 unique TR-units, but only a small fraction of them are shared with H. magnipapillata, M. brevicollis, or mammalian proteomes. The overall abundance of these TRs stands out relative to that of 14 proteomes representing the diversity among eukaryotes and within the metazoan world. TR-units are characterized by a unique composition of amino acids, with cysteine and histidine being over-represented. Structurally, most TR-segments are associated with coiled and disordered regions. Interestingly, 80% of the TR-segments can be read in more than one open reading frame. For over 100 of them, translation of the alternative frames would result in long proteins. Most domain families that are characterized as repeats in eukaryotes are found in the TR-proteomes from Nematostella and Hydra.While most TR-proteins have originated from prediction tools and are still awaiting experimental validations, supportive evidence exists for hundreds of TR-units in Nematostella. The existence of TR-proteins in early metazoan life may have served as a robust mode for novel genes with previously overlooked structural and functional characteristics." @default.
• W2029249531 created "2016-06-24" @default.
• W2029249531 creator A5028450191 @default.
• W2029249531 creator A5051946088 @default.
• W2029249531 creator A5085924022 @default.
• W2029249531 date "2009-12-01" @default.
• W2029249531 modified "2023-10-14" @default.
• W2029249531 title "Expansion of tandem repeats in sea anemone Nematostella vectensis proteome: A source for gene novelty?" @default.
• W2029249531 cites W1580522653 @default.
• W2029249531 cites W1632341477 @default.
• W2029249531 cites W1794209129 @default.
• W2029249531 cites W1981679111 @default.
• W2029249531 cites W1991731239 @default.
• W2029249531 cites W1994836540 @default.
• W2029249531 cites W2003062832 @default.
• W2029249531 cites W2007486980 @default.
• W2029249531 cites W2008494223 @default.
• W2029249531 cites W2008560636 @default.
• W2029249531 cites W2009815491 @default.
• W2029249531 cites W2011685215 @default.
• W2029249531 cites W2012196781 @default.
• W2029249531 cites W2027347467 @default.
• W2029249531 cites W2033837701 @default.
• W2029249531 cites W2054225539 @default.
• W2029249531 cites W2055382743 @default.
• W2029249531 cites W2060178110 @default.
• W2029249531 cites W2066688961 @default.
• W2029249531 cites W2067558229 @default.
• W2029249531 cites W2068503722 @default.
• W2029249531 cites W2068742942 @default.
• W2029249531 cites W2068986838 @default.
• W2029249531 cites W2074539100 @default.
• W2029249531 cites W2076870182 @default.
• W2029249531 cites W2095318832 @default.
• W2029249531 cites W2103148772 @default.
• W2029249531 cites W2105144801 @default.
• W2029249531 cites W2105961968 @default.
• W2029249531 cites W2107751776 @default.
• W2029249531 cites W2110114087 @default.
• W2029249531 cites W2117380529 @default.
• W2029249531 cites W2129328366 @default.
• W2029249531 cites W2136280642 @default.
• W2029249531 cites W2141656459 @default.
• W2029249531 cites W2146683382 @default.
• W2029249531 cites W2148312526 @default.
• W2029249531 cites W2151061073 @default.
• W2029249531 cites W2154406573 @default.
• W2029249531 cites W2155761693 @default.
• W2029249531 cites W2157190239 @default.
• W2029249531 cites W2158247578 @default.
• W2029249531 cites W2161732286 @default.
• W2029249531 cites W2162085776 @default.
• W2029249531 cites W2168475193 @default.
• W2029249531 cites W2168722817 @default.
• W2029249531 cites W2207678969 @default.
• W2029249531 cites W386603110 @default.
• W2029249531 cites W4207034695 @default.
• W2029249531 cites W4210968583 @default.
• W2029249531 cites W626692 @default.
• W2029249531 doi "https://doi.org/10.1186/1471-2164-10-593" @default.
• W2029249531 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2805694" @default.
• W2029249531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20003297" @default.
• W2029249531 hasPublicationYear "2009" @default.
• W2029249531 type Work @default.
• W2029249531 sameAs 2029249531 @default.
• W2029249531 citedByCount "7" @default.
• W2029249531 countsByYear W20292495312012 @default.
• W2029249531 countsByYear W20292495312016 @default.
• W2029249531 countsByYear W20292495312018 @default.
• W2029249531 countsByYear W20292495312022 @default.
• W2029249531 crossrefType "journal-article" @default.
• W2029249531 hasAuthorship W2029249531A5028450191 @default.
• W2029249531 hasAuthorship W2029249531A5051946088 @default.
• W2029249531 hasAuthorship W2029249531A5085924022 @default.
• W2029249531 hasBestOaLocation W20292495311 @default.
• W2029249531 hasConcept C104317684 @default.
• W2029249531 hasConcept C104397665 @default.
• W2029249531 hasConcept C141231307 @default.
• W2029249531 hasConcept C27149982 @default.
• W2029249531 hasConcept C2778089062 @default.
• W2029249531 hasConcept C34781881 @default.
• W2029249531 hasConcept C515207424 @default.
• W2029249531 hasConcept C54355233 @default.
• W2029249531 hasConcept C59822182 @default.
• W2029249531 hasConcept C70721500 @default.
• W2029249531 hasConcept C78458016 @default.
• W2029249531 hasConcept C86803240 @default.
• W2029249531 hasConcept C95444343 @default.
• W2029249531 hasConceptScore W2029249531C104317684 @default.
• W2029249531 hasConceptScore W2029249531C104397665 @default.
• W2029249531 hasConceptScore W2029249531C141231307 @default.
• W2029249531 hasConceptScore W2029249531C27149982 @default.
• W2029249531 hasConceptScore W2029249531C2778089062 @default.
• W2029249531 hasConceptScore W2029249531C34781881 @default.
• W2029249531 hasConceptScore W2029249531C515207424 @default.
• W2029249531 hasConceptScore W2029249531C54355233 @default.
• W2029249531 hasConceptScore W2029249531C59822182 @default.
• W2029249531 hasConceptScore W2029249531C70721500 @default.
• W2029249531 hasConceptScore W2029249531C78458016 @default.
• W2029249531 hasConceptScore W2029249531C86803240 @default.

• next