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- W2029265455 abstract "B cells become effective factories for antibody production only after they have gone through a series of maturation steps that select clones of B cells carrying somatic mutations for high-affinity antibody. This process takes place in the germinal center, where B cells are also thought to compete vigorously for available antigen. Using intravital microscopy, Allen et al. observed that the behavior of germinal center B cells is more consistent with a competition for the attention of helper T cells than for scarce antigen. This finding could prove useful in considering how best to stimulate robust immune responses with vaccines." @default.
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- W2029265455 date "2007-01-26" @default.
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- W2029265455 title "Inside B Cell Central" @default.
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