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- W2029272313 abstract "Several unusual cytogenetic changes have occurred during the evolution of chronic myelogenous leukemia in a 32-year-old white male with this disease for 8 years. The first appearance of a hypodiploid cell line containing a dicentric marker occurred 2 years after diagnosis and this line was eliminated by several courses of therapy with hydroxyurea. A second clone, which had a partial deletion of the long arm of one of the number 8 chromosomes (8q-) was noted a year later, but this line has been refractory to intensive combination chemotherapy." @default.
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- W2029272313 date "1976-01-01" @default.
- W2029272313 modified "2023-09-26" @default.
- W2029272313 title "Unusual Clonal Evolution in a Case of Chronic Myelogenous Leukemia" @default.
- W2029272313 doi "https://doi.org/10.1159/000207961" @default.
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