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• W2029279670 startingPage "85" @default.
• W2029279670 abstract "The synthesis of three analogues of 2′-5′-linked oligoriboadenylates is reported. Two trimers, having at the 2′-end a 3′-amino- (or 3′-tetradecanamido)-3′-deoxy-riboadenosine, were assembled via a phosphotriester approach. In the same way, we also prepared a tetramer carrying at the 2′-end β-L-riboadenosine instead of β-D-riboadenosine. The non-terminal building unit 3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)-N6-benzoyladenosine and the appropriately protected modified riboadenosines were coupled using the phosphorylating agent 2-chlorophenyl-O,O-bis(1-benzotriazolyl) phosphate. The removal of all protecting groups from the intermediate trimers and tetramer was effected by ammonolysis, followed by treatment with fluoride ions." @default.
• W2029279670 created "2016-06-24" @default.
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• W2029279670 date "1986-01-01" @default.
• W2029279670 modified "2023-10-09" @default.
• W2029279670 title "Synthesis of some modified 2′-5′-linked oligoriboadenylates of 2-5A core" @default.
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• W2029279670 doi "https://doi.org/10.1002/recl.19861050303" @default.
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