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- W2029320512 abstract "Laser speckle imaging (LSI) through a thinned skull over the somatosensory cortex was utilized to map the spatiotemporal characteristics of local cerebral flood flow (CBF) in anesthetized rats during sciatic nerve stimulation. Region-of-interest selection and Temporal clustering analysis (TCA) method was illustrated on the dataset from high-resolution optical imaging to detect the timing and location of CBF activation. Contralateral hindlimb sensory cortical microflow was activated to increase promptly in less than 1 s after the onset of 2 s electrical stimulation then evolved in different discrete regions. Individual arteries, veins and capillaries in different diameters were activated with the time going. This pattern is similar but slightly elaborated to the results obtained from laser Doppler flowmetry (LDF), functional magnetic resonance imaging (fMRI). We presented this combination to characterize the behaviors of CBF response to neuronal activity, which might possibly lead to a better understanding of neurovascular coupling and fMRI signals." @default.
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- W2029320512 date "2003-12-10" @default.
- W2029320512 modified "2023-09-27" @default.
- W2029320512 title "Characterization of cerebral blood flow response to sciatic nerve stimulation using laser speckle imaging" @default.
- W2029320512 doi "https://doi.org/10.1117/12.546573" @default.
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