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• W2029326415 abstract "The spindle checkpoint blocks cell-cycle progression until chromosomes are properly attached to the mitotic spindle. Popular models propose that checkpoint proteins associate with kinetochores to produce a wait anaphase signal that inhibits anaphase. Recent data suggest that a two-state switch results from using the same kinetochore proteins to bind microtubules and checkpoint proteins. At least eight protein kinases are implicated in spindle checkpoint signaling, arguing that a traditional signal transduction cascade is integral to spindle checkpoint signaling." @default.
• W2029326415 created "2016-06-24" @default.
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• W2029326415 creator A5072633316 @default.
• W2029326415 date "2008-04-01" @default.
• W2029326415 modified "2023-09-30" @default.
• W2029326415 title "Linking Kinetochore-Microtubule Binding to the Spindle Checkpoint" @default.
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• W2029326415 doi "https://doi.org/10.1016/j.devcel.2008.03.015" @default.
• W2029326415 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2696048" @default.
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