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- W2029328096 abstract "The increase in sensitivity of frog photoreceptors after illumination, hypersensitivity, was studied by recording fast-PIII responses of the isolated bull frog retina superfused with physiological saline containing 5 mM sodium aspartate. The hypersensitivity is mot marked after illumination which bleaches only 0.01% of the rhodopsin initially present. The wavelength of light, which is optimum to induce the hypersensitivity, is about 500 nm. Several kinds of phosphodiesterase inhibitors, isobutylmethylxanthine (IBMX), papaverine, theophylline and caffeine act to induce the hypersensitivity, as does lowered extracellular concentrations of calcium ion, [Ca2+]out. Such action of phosphodiesterase inhibitor can be antagonized by an increase in [Ca2+]out. The relation between effects of Ca2+ and cyclic nucleotides on photoreceptor is discussed." @default.
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- W2029328096 date "1982-01-01" @default.
- W2029328096 modified "2023-10-02" @default.
- W2029328096 title "The action of phosphodiesterase inhibitors on the hypersensitivity of frog photoreceptor" @default.
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- W2029328096 doi "https://doi.org/10.1016/0042-6989(82)90176-6" @default.
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