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- W2029332005 abstract "Dietary exposure to the bovine spongiform encephalopathy (BSE) agent is the probable cause of variant Creutzfeldt-Jakob disease in people. The industrial manufacturing process for the production of gelatine and colloidal protein by the heat and pressure process was downscaled accurately and its capacity to remove or inactivate bse infectivity was investigated. Gelatine was made from bones experimentally contaminated with mouse brain infected with the 301V strain of mouse-passaged bse agent in which the infective titre was 10(8.7) ID50/g. No infectivity was detected in the extracted protein (> or =10(0.45) ID50/g), and the calculated clearance factor was 10(6.5) ID50 or more." @default.
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- W2029332005 date "2005-09-01" @default.
- W2029332005 modified "2023-09-26" @default.
- W2029332005 title "Inactivation of the BSE agent by the heat and pressure process for manufacturing gelatine" @default.
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- W2029332005 doi "https://doi.org/10.1136/vr.157.10.277" @default.
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