FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029334407> ?p ?o ?g. }

• W2029334407 endingPage "577" @default.
• W2029334407 startingPage "565" @default.
• W2029334407 abstract "The levels of some enzymatic activities involved in protoheme synthesis have been measured in subcellular fractions obtained at different stages of the growth of the yeast Saccharomyces cerevisiae grown anaerobically and aerobically with glucose (50 or 6 g/ liter), and ethanol (20 g/liter) as the carbon source. The degree of repression of the respiratory system is estimated by the respiratory capacity of whole cells, by the activities of succinate-cytochrome c reductase and cytochrome c oxidase of the mitochondrial particles, and by the cytochrome spectra. The results show that (i) the more porphyrins (cytochromes) that are synthesized by the cells, the lower is the specific activity of δ-aminolevulinic acid (ALA) synthetase and the higher is the specific activity of ALA dehydratase, the activity ratio ALA synthetase/ALA dehydratase decreasing at least 10-fold compared to the repressed cells; (ii) the amount of intracellular ALA found under all conditions tested (from 0.05 to 1.5 mm in the cell sap) correlates well with the measured ALA synthetase activity; its presence argues against a rate-limiting function for ALA synthetase and rather favors such a role for the ALA dehydratase in the formation of heme in yeast; (iii) the rate of porphyrin synthesis measured in vitro is higher in the case of cells with high cytochrome contents; and (iv) the specific activities of succinyl CoA synthetase and protoheme ferrolyase are always present in nonlimiting amounts. Some experiments are described showing that the values of the activities which are calculated from these in situ and in vivo experiments compare well with the values measured in vitro in the acellular extracts. The results concerning the enzymatic activities, together with (i) the excretion of coproporphyrin(ogen) and the accumulation of protoporphyrin + Zn-protoporphyrin in anaerobiosis, (ii) the presence of protoporpho(di)methene (P503) in anaerobic and repressed cells, and (iii) the presence of intracellular ALA under all growth conditions, are discussed in terms of possible control(s) of heme synthesis in yeast." @default.
• W2029334407 created "2016-06-24" @default.
• W2029334407 creator A5000532824 @default.
• W2029334407 creator A5029211184 @default.
• W2029334407 date "1977-03-01" @default.
• W2029334407 modified "2023-09-30" @default.
• W2029334407 title "Changes in the activities of the protoheme-synthesizing system during the growth of yeast under different conditions" @default.
• W2029334407 cites W1023089740 @default.
• W2029334407 cites W1479367516 @default.
• W2029334407 cites W1480456677 @default.
• W2029334407 cites W1510367532 @default.
• W2029334407 cites W1524077291 @default.
• W2029334407 cites W1547207533 @default.
• W2029334407 cites W1554023844 @default.
• W2029334407 cites W1591909631 @default.
• W2029334407 cites W1603501938 @default.
• W2029334407 cites W1640491587 @default.
• W2029334407 cites W1739192257 @default.
• W2029334407 cites W1773246693 @default.
• W2029334407 cites W1775749144 @default.
• W2029334407 cites W1878915947 @default.
• W2029334407 cites W1976214490 @default.
• W2029334407 cites W1976600497 @default.
• W2029334407 cites W1984059898 @default.
• W2029334407 cites W1985725345 @default.
• W2029334407 cites W1995402967 @default.
• W2029334407 cites W1995710377 @default.
• W2029334407 cites W1996153140 @default.
• W2029334407 cites W1998972954 @default.
• W2029334407 cites W2015387867 @default.
• W2029334407 cites W2020088149 @default.
• W2029334407 cites W2020663371 @default.
• W2029334407 cites W2021289001 @default.
• W2029334407 cites W2021653404 @default.
• W2029334407 cites W2025426022 @default.
• W2029334407 cites W2025728679 @default.
• W2029334407 cites W2028681471 @default.
• W2029334407 cites W2029182783 @default.
• W2029334407 cites W2033393651 @default.
• W2029334407 cites W2033427834 @default.
• W2029334407 cites W2038418682 @default.
• W2029334407 cites W2058464164 @default.
• W2029334407 cites W2061106778 @default.
• W2029334407 cites W2064170352 @default.
• W2029334407 cites W2068597663 @default.
• W2029334407 cites W2073711204 @default.
• W2029334407 cites W2079591243 @default.
• W2029334407 cites W2121818387 @default.
• W2029334407 cites W2143834288 @default.
• W2029334407 cites W2175651785 @default.
• W2029334407 cites W2247086922 @default.
• W2029334407 cites W2283398556 @default.
• W2029334407 cites W2286715846 @default.
• W2029334407 cites W2319355334 @default.
• W2029334407 cites W2319770561 @default.
• W2029334407 cites W2325406791 @default.
• W2029334407 cites W2338223451 @default.
• W2029334407 cites W2342448571 @default.
• W2029334407 cites W2403381490 @default.
• W2029334407 cites W2405562385 @default.
• W2029334407 cites W2415809783 @default.
• W2029334407 cites W3206464715 @default.
• W2029334407 cites W40113957 @default.
• W2029334407 cites W2037092822 @default.
• W2029334407 cites W2283923783 @default.
• W2029334407 doi "https://doi.org/10.1016/0003-9861(77)90145-x" @default.
• W2029334407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/192152" @default.
• W2029334407 hasPublicationYear "1977" @default.
• W2029334407 type Work @default.
• W2029334407 sameAs 2029334407 @default.
• W2029334407 citedByCount "45" @default.
• W2029334407 crossrefType "journal-article" @default.
• W2029334407 hasAuthorship W2029334407A5000532824 @default.
• W2029334407 hasAuthorship W2029334407A5029211184 @default.
• W2029334407 hasConcept C123249941 @default.
• W2029334407 hasConcept C181199279 @default.
• W2029334407 hasConcept C185592680 @default.
• W2029334407 hasConcept C198684833 @default.
• W2029334407 hasConcept C20705724 @default.
• W2029334407 hasConcept C2776217839 @default.
• W2029334407 hasConcept C2777576037 @default.
• W2029334407 hasConcept C2779222958 @default.
• W2029334407 hasConcept C2779480358 @default.
• W2029334407 hasConcept C2780768313 @default.
• W2029334407 hasConcept C2781374117 @default.
• W2029334407 hasConcept C28859421 @default.
• W2029334407 hasConcept C29311851 @default.
• W2029334407 hasConcept C38485361 @default.
• W2029334407 hasConcept C55493867 @default.
• W2029334407 hasConcept C86803240 @default.
• W2029334407 hasConceptScore W2029334407C123249941 @default.
• W2029334407 hasConceptScore W2029334407C181199279 @default.
• W2029334407 hasConceptScore W2029334407C185592680 @default.
• W2029334407 hasConceptScore W2029334407C198684833 @default.
• W2029334407 hasConceptScore W2029334407C20705724 @default.
• W2029334407 hasConceptScore W2029334407C2776217839 @default.
• W2029334407 hasConceptScore W2029334407C2777576037 @default.
• W2029334407 hasConceptScore W2029334407C2779222958 @default.

• next