Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029346762> ?p ?o ?g. }
- W2029346762 endingPage "345" @default.
- W2029346762 startingPage "338" @default.
- W2029346762 abstract "Summary Gene ablation studies in mice indicate that lymphotoxin (LT)α, LTβ and LTβR are essential for the genesis of lymph nodes (LN), normal structural development of peripheral lymphoid tissues and the differentiation of natural killer (NK) cells. LTβR binds to the heterotrimeric cytokines LT α1β2 and LIGHT. LTs also regulate stromal cell expression of lymphocyte homing chemokines. Uterine decidualization in normal (+/+) mice is accompanied by the appearance and maturation of large numbers of uterine NK (uNK) cells that differentiate from precursors mobilized to the uterus from secondary lymphoid tissues. uNK cells accumulate in a transient, lymphocyte‐rich region known as the metrial gland or, more recently, the mesometrial lymphoid aggregrate of pregnancy (MLAp). To determine if LTs contribute to development of the MLAp, and to the differentiation and/or localization of uNK cells, a histological study was undertaken of implantation sites from LTα null, LTβR null and gestation day‐matched, normal mice. Implantation sites from the gene‐ablated mice contained abundant numbers of uNK cells that localized appropriately. This indicates that the stromally derived molecules supporting NK cell differentiation in the uterus differ from those used in secondary lymphoid organs." @default.
- W2029346762 created "2016-06-24" @default.
- W2029346762 creator A5007367790 @default.
- W2029346762 creator A5017484182 @default.
- W2029346762 creator A5029115834 @default.
- W2029346762 creator A5033085250 @default.
- W2029346762 creator A5045652188 @default.
- W2029346762 creator A5064853060 @default.
- W2029346762 creator A5065178403 @default.
- W2029346762 creator A5090506123 @default.
- W2029346762 date "2003-02-25" @default.
- W2029346762 modified "2023-10-14" @default.
- W2029346762 title "Neither lymphotoxin alpha nor lymphotoxin beta receptor expression is required for biogenesis of lymphoid aggregates or differentiation of natural killer cells in the pregnant mouse uterus" @default.
- W2029346762 cites W146089551 @default.
- W2029346762 cites W1508336615 @default.
- W2029346762 cites W1705862960 @default.
- W2029346762 cites W1875554126 @default.
- W2029346762 cites W1963627373 @default.
- W2029346762 cites W1964930836 @default.
- W2029346762 cites W1972195950 @default.
- W2029346762 cites W1973891072 @default.
- W2029346762 cites W1988547097 @default.
- W2029346762 cites W1994637673 @default.
- W2029346762 cites W1997044780 @default.
- W2029346762 cites W2009550948 @default.
- W2029346762 cites W2011929088 @default.
- W2029346762 cites W2018366686 @default.
- W2029346762 cites W2019547929 @default.
- W2029346762 cites W2019883580 @default.
- W2029346762 cites W2029102440 @default.
- W2029346762 cites W2041354260 @default.
- W2029346762 cites W2050790947 @default.
- W2029346762 cites W2050828232 @default.
- W2029346762 cites W2088094253 @default.
- W2029346762 cites W2093135399 @default.
- W2029346762 cites W2101580628 @default.
- W2029346762 cites W2113765407 @default.
- W2029346762 cites W2120798610 @default.
- W2029346762 cites W2121997180 @default.
- W2029346762 cites W2137792946 @default.
- W2029346762 cites W2141295972 @default.
- W2029346762 cites W2147496720 @default.
- W2029346762 cites W2150130423 @default.
- W2029346762 cites W2154155318 @default.
- W2029346762 cites W2157265156 @default.
- W2029346762 cites W2167818435 @default.
- W2029346762 cites W2171501214 @default.
- W2029346762 cites W2186364420 @default.
- W2029346762 cites W4229618597 @default.
- W2029346762 cites W4230665698 @default.
- W2029346762 cites W4231950847 @default.
- W2029346762 doi "https://doi.org/10.1046/j.1365-2567.2003.01586.x" @default.
- W2029346762 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1782905" @default.
- W2029346762 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12603600" @default.
- W2029346762 hasPublicationYear "2003" @default.
- W2029346762 type Work @default.
- W2029346762 sameAs 2029346762 @default.
- W2029346762 citedByCount "16" @default.
- W2029346762 countsByYear W20293467622013 @default.
- W2029346762 countsByYear W20293467622015 @default.
- W2029346762 countsByYear W20293467622017 @default.
- W2029346762 countsByYear W20293467622019 @default.
- W2029346762 countsByYear W20293467622020 @default.
- W2029346762 crossrefType "journal-article" @default.
- W2029346762 hasAuthorship W2029346762A5007367790 @default.
- W2029346762 hasAuthorship W2029346762A5017484182 @default.
- W2029346762 hasAuthorship W2029346762A5029115834 @default.
- W2029346762 hasAuthorship W2029346762A5033085250 @default.
- W2029346762 hasAuthorship W2029346762A5045652188 @default.
- W2029346762 hasAuthorship W2029346762A5064853060 @default.
- W2029346762 hasAuthorship W2029346762A5065178403 @default.
- W2029346762 hasAuthorship W2029346762A5090506123 @default.
- W2029346762 hasBestOaLocation W20293467621 @default.
- W2029346762 hasConcept C109159458 @default.
- W2029346762 hasConcept C125864771 @default.
- W2029346762 hasConcept C134018914 @default.
- W2029346762 hasConcept C154317977 @default.
- W2029346762 hasConcept C16930146 @default.
- W2029346762 hasConcept C17991360 @default.
- W2029346762 hasConcept C181152851 @default.
- W2029346762 hasConcept C202751555 @default.
- W2029346762 hasConcept C203014093 @default.
- W2029346762 hasConcept C2777761686 @default.
- W2029346762 hasConcept C2778102761 @default.
- W2029346762 hasConcept C2778316770 @default.
- W2029346762 hasConcept C2779066055 @default.
- W2029346762 hasConcept C28328180 @default.
- W2029346762 hasConcept C502942594 @default.
- W2029346762 hasConcept C55493867 @default.
- W2029346762 hasConcept C61879462 @default.
- W2029346762 hasConcept C79904392 @default.
- W2029346762 hasConcept C86803240 @default.
- W2029346762 hasConcept C95444343 @default.
- W2029346762 hasConceptScore W2029346762C109159458 @default.
- W2029346762 hasConceptScore W2029346762C125864771 @default.
- W2029346762 hasConceptScore W2029346762C134018914 @default.
- W2029346762 hasConceptScore W2029346762C154317977 @default.
- W2029346762 hasConceptScore W2029346762C16930146 @default.