FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029352148> ?p ?o ?g. }

• W2029352148 endingPage "2142" @default.
• W2029352148 startingPage "2136" @default.
• W2029352148 abstract "Objective: The authors investigated the temporal and spatial characteristics of pattern electroretinogram (PERG) and spatial contrast sensitivity (CS) in primary congenital glaucoma (PCG) to determine whether the PERG and CS could be useful tools in the diagnosis of childhood glaucoma, especially PCG. Participants: The PERGs were evaluated in eyes from ten patients with PCG and nine age-matched visually normal subjects. Intervention: All patients received complete ophthalmologic evaluations including visual field testing. Main Outcome Measures: The PERGs were recorded using phase-alternating (2, 4, and 16 reversals per second [rps]) checkerboard patterns (30' and 60' checks). Results: The patients with PCG exhibited decreased CS when compared with that of control subjects. Significant PERG deficits also were detected in these patients. However, PERG amplitude in patients with PCG almost reached control subject levels at high (16 rps) temporal frequency. This was true for both 30' and 60' checks. Taken together, these observations on PERG amplitude suggest a more important deficiency of the neural response of the retinal cells at lower temporal frequency (rps) in patients with PCG. This is unlike primary open-angle glaucoma (POAG) in which significant PERG deficits are observed at high temporal frequencies. Conclusions: The PERG amplitude is reduced in patients with PCG, and this is consistent with a loss of CS and visual field changes in these patients. However, the spatiotemporal characteristics of the PERG deficits in PCG differ from those of POAG. This could suggest a difference in the mechanisms mediating retinal ganglion cell dysfunction in the two types of glaucoma. Objective: The authors investigated the temporal and spatial characteristics of pattern electroretinogram (PERG) and spatial contrast sensitivity (CS) in primary congenital glaucoma (PCG) to determine whether the PERG and CS could be useful tools in the diagnosis of childhood glaucoma, especially PCG. Participants: The PERGs were evaluated in eyes from ten patients with PCG and nine age-matched visually normal subjects. Intervention: All patients received complete ophthalmologic evaluations including visual field testing. Main Outcome Measures: The PERGs were recorded using phase-alternating (2, 4, and 16 reversals per second [rps]) checkerboard patterns (30' and 60' checks). Results: The patients with PCG exhibited decreased CS when compared with that of control subjects. Significant PERG deficits also were detected in these patients. However, PERG amplitude in patients with PCG almost reached control subject levels at high (16 rps) temporal frequency. This was true for both 30' and 60' checks. Taken together, these observations on PERG amplitude suggest a more important deficiency of the neural response of the retinal cells at lower temporal frequency (rps) in patients with PCG. This is unlike primary open-angle glaucoma (POAG) in which significant PERG deficits are observed at high temporal frequencies. Conclusions: The PERG amplitude is reduced in patients with PCG, and this is consistent with a loss of CS and visual field changes in these patients. However, the spatiotemporal characteristics of the PERG deficits in PCG differ from those of POAG. This could suggest a difference in the mechanisms mediating retinal ganglion cell dysfunction in the two types of glaucoma." @default.
• W2029352148 created "2016-06-24" @default.
• W2029352148 creator A5055126875 @default.
• W2029352148 creator A5059285706 @default.
• W2029352148 creator A5065141532 @default.
• W2029352148 creator A5090865160 @default.
• W2029352148 creator A5091061957 @default.
• W2029352148 date "1997-12-01" @default.
• W2029352148 modified "2023-09-23" @default.
• W2029352148 title "Pattern Electroretinogram and Spatial Contrast Sensitivity in Primary Congenital Glaucoma" @default.
• W2029352148 cites W1964458657 @default.
• W2029352148 cites W1970428486 @default.
• W2029352148 cites W1993051562 @default.
• W2029352148 cites W2014166827 @default.
• W2029352148 cites W2015074583 @default.
• W2029352148 cites W2024679584 @default.
• W2029352148 cites W2031895914 @default.
• W2029352148 cites W2032445406 @default.
• W2029352148 cites W2061974995 @default.
• W2029352148 cites W2063729668 @default.
• W2029352148 cites W2066001647 @default.
• W2029352148 cites W2074472425 @default.
• W2029352148 cites W2079978641 @default.
• W2029352148 cites W2116153835 @default.
• W2029352148 doi "https://doi.org/10.1016/s0161-6420(97)30049-9" @default.
• W2029352148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9400776" @default.
• W2029352148 hasPublicationYear "1997" @default.
• W2029352148 type Work @default.
• W2029352148 sameAs 2029352148 @default.
• W2029352148 citedByCount "2" @default.
• W2029352148 countsByYear W20293521482020 @default.
• W2029352148 crossrefType "journal-article" @default.
• W2029352148 hasAuthorship W2029352148A5055126875 @default.
• W2029352148 hasAuthorship W2029352148A5059285706 @default.
• W2029352148 hasAuthorship W2029352148A5065141532 @default.
• W2029352148 hasAuthorship W2029352148A5090865160 @default.
• W2029352148 hasAuthorship W2029352148A5091061957 @default.
• W2029352148 hasConcept C100921725 @default.
• W2029352148 hasConcept C118487528 @default.
• W2029352148 hasConcept C119767625 @default.
• W2029352148 hasConcept C120665830 @default.
• W2029352148 hasConcept C121332964 @default.
• W2029352148 hasConcept C15744967 @default.
• W2029352148 hasConcept C169760540 @default.
• W2029352148 hasConcept C2776058522 @default.
• W2029352148 hasConcept C2776502983 @default.
• W2029352148 hasConcept C2777093970 @default.
• W2029352148 hasConcept C2778527774 @default.
• W2029352148 hasConcept C2779113765 @default.
• W2029352148 hasConcept C2780827179 @default.
• W2029352148 hasConcept C548259974 @default.
• W2029352148 hasConcept C71924100 @default.
• W2029352148 hasConceptScore W2029352148C100921725 @default.
• W2029352148 hasConceptScore W2029352148C118487528 @default.
• W2029352148 hasConceptScore W2029352148C119767625 @default.
• W2029352148 hasConceptScore W2029352148C120665830 @default.
• W2029352148 hasConceptScore W2029352148C121332964 @default.
• W2029352148 hasConceptScore W2029352148C15744967 @default.
• W2029352148 hasConceptScore W2029352148C169760540 @default.
• W2029352148 hasConceptScore W2029352148C2776058522 @default.
• W2029352148 hasConceptScore W2029352148C2776502983 @default.
• W2029352148 hasConceptScore W2029352148C2777093970 @default.
• W2029352148 hasConceptScore W2029352148C2778527774 @default.
• W2029352148 hasConceptScore W2029352148C2779113765 @default.
• W2029352148 hasConceptScore W2029352148C2780827179 @default.
• W2029352148 hasConceptScore W2029352148C548259974 @default.
• W2029352148 hasConceptScore W2029352148C71924100 @default.
• W2029352148 hasIssue "12" @default.
• W2029352148 hasLocation W20293521481 @default.
• W2029352148 hasLocation W20293521482 @default.
• W2029352148 hasOpenAccess W2029352148 @default.
• W2029352148 hasPrimaryLocation W20293521481 @default.
• W2029352148 hasRelatedWork W2010788813 @default.
• W2029352148 hasRelatedWork W2052304484 @default.
• W2029352148 hasRelatedWork W2061322523 @default.
• W2029352148 hasRelatedWork W2109633129 @default.
• W2029352148 hasRelatedWork W2170858921 @default.
• W2029352148 hasRelatedWork W2574752693 @default.
• W2029352148 hasRelatedWork W2582186280 @default.
• W2029352148 hasRelatedWork W2972928644 @default.
• W2029352148 hasRelatedWork W3030369144 @default.
• W2029352148 hasRelatedWork W3122090364 @default.
• W2029352148 hasVolume "104" @default.
• W2029352148 isParatext "false" @default.
• W2029352148 isRetracted "false" @default.
• W2029352148 magId "2029352148" @default.
• W2029352148 workType "article" @default.