FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029353358> ?p ?o ?g. }

• W2029353358 endingPage "887" @default.
• W2029353358 startingPage "867" @default.
• W2029353358 abstract "Cardiovascular disease is the leading cause of death in women but manifests itself primarily in the postmenopausal years. Menopause appears to increase the cardiovascular risk, at least when surgically induced, whereas the effects of the natural menopause are still a matter of debate. Why postmenopausal women apparently lose their natural cardioprotection is not established, but oestrogen deficiency seems to play an important role. Loss of ovarian hormone production at the menopause significantly alters serum lipids and lipoproteins, giving rise to more atherogenic lipid profiles throughout the postmenopausal years, and these changes may in part be responsible for the alleged cardiovascular risk. Postmenopausal hormone replacement therapy, using oral unopposed oestrogens, induces potential favourable effects on lipids and lipoproteins, and epidemiological evidence has established that the risk of cardiovascular mortality is reduced by 40–60% in women receiving postmenopausal oestrogen therapy. Part of this reduction seems to be explained by changes in lipids and lipoproteins. Parenteral administration of oestrogens induces comparable, although less pronounced effects on lipids and lipoproteins, and the possible cardioprotective role of parenteral administration remains obscure. The addition of progestogens to postmenopausal oestrogen therapy is essential for endometrial protection, but progestogens apparently antagonize some of the actions of oestrogens on lipid metabolism. However, the type, the dose, the duration and the route of administration, as well as the potency balance between the oestrogen and the progestogen employed, are important determinants for the ultimate effect on lipid metabolism. With the use of cyclic administration and the lowest possible doses of progestogens, the oestrogenic actions on lipids and lipoproteins can be largely preserved, but the cardioprotective potential of combined oestrogenprogestogen therapy is as yet unknown." @default.
• W2029353358 created "2016-06-24" @default.
• W2029353358 creator A5089511718 @default.
• W2029353358 date "1991-12-01" @default.
• W2029353358 modified "2023-10-11" @default.
• W2029353358 title "8 Effects of sex steroids on serum lipids and lipoproteins" @default.
• W2029353358 cites W1494381085 @default.
• W2029353358 cites W1511583411 @default.
• W2029353358 cites W1552709412 @default.
• W2029353358 cites W1577432369 @default.
• W2029353358 cites W17105541 @default.
• W2029353358 cites W1785735331 @default.
• W2029353358 cites W1957397409 @default.
• W2029353358 cites W1966594148 @default.
• W2029353358 cites W1967030964 @default.
• W2029353358 cites W1970378446 @default.
• W2029353358 cites W1972007569 @default.
• W2029353358 cites W1972751614 @default.
• W2029353358 cites W1973037092 @default.
• W2029353358 cites W1974580748 @default.
• W2029353358 cites W1978269733 @default.
• W2029353358 cites W1979625320 @default.
• W2029353358 cites W1981543445 @default.
• W2029353358 cites W1983170818 @default.
• W2029353358 cites W1986932337 @default.
• W2029353358 cites W1986961735 @default.
• W2029353358 cites W1989258056 @default.
• W2029353358 cites W1989498280 @default.
• W2029353358 cites W1989850352 @default.
• W2029353358 cites W1991907434 @default.
• W2029353358 cites W1993800602 @default.
• W2029353358 cites W1994920226 @default.
• W2029353358 cites W1997141513 @default.
• W2029353358 cites W1998816720 @default.
• W2029353358 cites W2003179352 @default.
• W2029353358 cites W2004882537 @default.
• W2029353358 cites W2005160956 @default.
• W2029353358 cites W2006104254 @default.
• W2029353358 cites W2007841512 @default.
• W2029353358 cites W2010657017 @default.
• W2029353358 cites W2018412468 @default.
• W2029353358 cites W2020947810 @default.
• W2029353358 cites W2021228627 @default.
• W2029353358 cites W2023116083 @default.
• W2029353358 cites W2026453151 @default.
• W2029353358 cites W2026845568 @default.
• W2029353358 cites W2027903952 @default.
• W2029353358 cites W2031141001 @default.
• W2029353358 cites W2034781215 @default.
• W2029353358 cites W2036591209 @default.
• W2029353358 cites W2037982368 @default.
• W2029353358 cites W2039904040 @default.
• W2029353358 cites W2044084677 @default.
• W2029353358 cites W2046802965 @default.
• W2029353358 cites W2049873194 @default.
• W2029353358 cites W2052182266 @default.
• W2029353358 cites W2053949446 @default.
• W2029353358 cites W2054097500 @default.
• W2029353358 cites W2062226970 @default.
• W2029353358 cites W2066637052 @default.
• W2029353358 cites W2067803293 @default.
• W2029353358 cites W2068050187 @default.
• W2029353358 cites W2068594223 @default.
• W2029353358 cites W2069304371 @default.
• W2029353358 cites W2073009604 @default.
• W2029353358 cites W2074289506 @default.
• W2029353358 cites W2080585365 @default.
• W2029353358 cites W2085559421 @default.
• W2029353358 cites W2089144240 @default.
• W2029353358 cites W2091159054 @default.
• W2029353358 cites W2094768566 @default.
• W2029353358 cites W2111208312 @default.
• W2029353358 cites W2112698709 @default.
• W2029353358 cites W2118890497 @default.
• W2029353358 cites W2119587778 @default.
• W2029353358 cites W2120955256 @default.
• W2029353358 cites W2122080406 @default.
• W2029353358 cites W2142173846 @default.
• W2029353358 cites W2144251744 @default.
• W2029353358 cites W2150683930 @default.
• W2029353358 cites W2152408579 @default.
• W2029353358 cites W2159073955 @default.
• W2029353358 cites W2167396895 @default.
• W2029353358 cites W2313867282 @default.
• W2029353358 cites W2335854637 @default.
• W2029353358 cites W2338124628 @default.
• W2029353358 cites W2341031326 @default.
• W2029353358 cites W2399189465 @default.
• W2029353358 cites W3022017015 @default.
• W2029353358 cites W4242382895 @default.
• W2029353358 cites W4254363271 @default.
• W2029353358 cites W4294294184 @default.
• W2029353358 cites W4296976561 @default.
• W2029353358 cites W4376522634 @default.
• W2029353358 doi "https://doi.org/10.1016/s0950-3552(05)80294-9" @default.
• W2029353358 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1822824" @default.
• W2029353358 hasPublicationYear "1991" @default.
• W2029353358 type Work @default.

• next