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- W2029371123 abstract "Two theoretical models for lipoprotein particle structure are proposed, based on density and composition and utilizing the Stokes' coefficient as evaluated from the Maude-Whitemore expression, using analytical ultracentrifugation. These density and composition models are compared with the Corey-Pauling-Koltun space-filling model proposed by Verdery and Nichols, and that proposed by Shen et al., which has a sharply defined boundary between the hydrophobic core and the amphipathic layer surrounding it. Results of our calculations of the percentage of total apolar lipid accommodated in the outer hydrophobic core −28. 64 and 94% for LDL, HDL2 and HDL3, respectively-suggest that there may he differences among these three lipoprotein classes in both the packing of cholesteryl ester and triglyceride as well as the conformation of apolipoproteins at the particle's surface." @default.
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- W2029371123 date "2006-01-01" @default.
- W2029371123 modified "2023-09-26" @default.
- W2029371123 title "We-P14:421 Apolipoprotein E4 allele is a genetic factor which contributes to plasma cholesterol responsiveness to diet therapy in type 2 diabetic patients" @default.
- W2029371123 doi "https://doi.org/10.1016/s1567-5688(06)81774-5" @default.
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