FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029372231> ?p ?o ?g. }

• W2029372231 endingPage "99" @default.
• W2029372231 startingPage "93" @default.
• W2029372231 abstract "To assess serum levels of B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) to determine their correlations with disease activity in pediatric systemic lupus erythematosus (pSLE) and juvenile idiopathic arthritis (JIA) patients. Twenty-nine pSLE patients and 33 JIA patients were recruited. SLE disease activity was assessed using the systemic lupus erythematosus disease activity index (SLEDAI), while the juvenile arthritis 27 joint disease activity score (JADAS-27) was calculated for JIA patients. Serum samples were assayed for BLyS and APRIL by the enzyme linked immunosorbent assay (ELISA). Serum BLyS and APRIL were elevated in both pSLE and JIA patients compared to controls. Serum BLyS levels correlated with both SLE and JIA disease activity (p = 0.042, p = 0.019, respectively) whereas serum APRIL levels correlated positively with JADAS-27 and inversely with SLEDAI (p = 0.001, p = 0.02, respectively). Elevated serum BLyS and APRIL were significantly associated with a lower incidence of nephritis (p = 0.043, p = 0.016, respectively), while elevated serum APRIL significantly associated with negative anti-dsDNA in pSLE patients (p = 0.017). In JIA patients, both serum BLyS and APRIL were significantly associated with the presence of ANA (p = 0.008, p < 0.001, respectively), while high serum APRIL associated with the presence of RF (p = 0.035). APRIL and BLYS levels correlated with each other positively in JIA but inversely in pSLE patients. Serum BLyS showed elevated levels that correlated significantly with pSLE and JIA disease activity, accordingly anti-BLyS therapy might be of great benefit to offset disease flare. The inverse correlations observed between APRIL with both BLyS and disease activity in pSLE patients raises the possibility of being a down regulator of the disease process." @default.
• W2029372231 created "2016-06-24" @default.
• W2029372231 creator A5010244843 @default.
• W2029372231 creator A5022115567 @default.
• W2029372231 creator A5052443691 @default.
• W2029372231 creator A5061452534 @default.
• W2029372231 creator A5076595275 @default.
• W2029372231 date "2014-04-01" @default.
• W2029372231 modified "2023-10-14" @default.
• W2029372231 title "Serum BLyS and APRIL as possible indicators of disease activity in pediatric systemic lupus erythematosus and juvenile idiopathic arthritis" @default.
• W2029372231 cites W1518008196 @default.
• W2029372231 cites W1520625797 @default.
• W2029372231 cites W1529215844 @default.
• W2029372231 cites W1642392901 @default.
• W2029372231 cites W1920115643 @default.
• W2029372231 cites W1966362133 @default.
• W2029372231 cites W1974684745 @default.
• W2029372231 cites W1975085076 @default.
• W2029372231 cites W1977195099 @default.
• W2029372231 cites W1986196545 @default.
• W2029372231 cites W1993388709 @default.
• W2029372231 cites W1998843795 @default.
• W2029372231 cites W1999098793 @default.
• W2029372231 cites W2014956545 @default.
• W2029372231 cites W2015881847 @default.
• W2029372231 cites W2024714476 @default.
• W2029372231 cites W2029980677 @default.
• W2029372231 cites W2030251794 @default.
• W2029372231 cites W2033296455 @default.
• W2029372231 cites W2035657152 @default.
• W2029372231 cites W2038420589 @default.
• W2029372231 cites W2044394416 @default.
• W2029372231 cites W2044907680 @default.
• W2029372231 cites W2054080837 @default.
• W2029372231 cites W2058853603 @default.
• W2029372231 cites W2064999867 @default.
• W2029372231 cites W2068543217 @default.
• W2029372231 cites W2087274273 @default.
• W2029372231 cites W2102002623 @default.
• W2029372231 cites W2118994799 @default.
• W2029372231 cites W2119170361 @default.
• W2029372231 cites W2122507029 @default.
• W2029372231 cites W2134389576 @default.
• W2029372231 cites W2134666735 @default.
• W2029372231 cites W2141467845 @default.
• W2029372231 cites W2146203649 @default.
• W2029372231 cites W2157130851 @default.
• W2029372231 cites W2169972660 @default.
• W2029372231 doi "https://doi.org/10.1016/j.ejr.2013.11.001" @default.
• W2029372231 hasPublicationYear "2014" @default.
• W2029372231 type Work @default.
• W2029372231 sameAs 2029372231 @default.
• W2029372231 citedByCount "4" @default.
• W2029372231 countsByYear W20293722312014 @default.
• W2029372231 countsByYear W20293722312018 @default.
• W2029372231 countsByYear W20293722312020 @default.
• W2029372231 countsByYear W20293722312023 @default.
• W2029372231 crossrefType "journal-article" @default.
• W2029372231 hasAuthorship W2029372231A5010244843 @default.
• W2029372231 hasAuthorship W2029372231A5022115567 @default.
• W2029372231 hasAuthorship W2029372231A5052443691 @default.
• W2029372231 hasAuthorship W2029372231A5061452534 @default.
• W2029372231 hasAuthorship W2029372231A5076595275 @default.
• W2029372231 hasBestOaLocation W20293722311 @default.
• W2029372231 hasConcept C126322002 @default.
• W2029372231 hasConcept C149443304 @default.
• W2029372231 hasConcept C159654299 @default.
• W2029372231 hasConcept C163764329 @default.
• W2029372231 hasConcept C170286685 @default.
• W2029372231 hasConcept C203014093 @default.
• W2029372231 hasConcept C2775915377 @default.
• W2029372231 hasConcept C2776670291 @default.
• W2029372231 hasConcept C2776912625 @default.
• W2029372231 hasConcept C2777077863 @default.
• W2029372231 hasConcept C2778453870 @default.
• W2029372231 hasConcept C2778674544 @default.
• W2029372231 hasConcept C2779075594 @default.
• W2029372231 hasConcept C2779134260 @default.
• W2029372231 hasConcept C2779912601 @default.
• W2029372231 hasConcept C71924100 @default.
• W2029372231 hasConcept C90924648 @default.
• W2029372231 hasConceptScore W2029372231C126322002 @default.
• W2029372231 hasConceptScore W2029372231C149443304 @default.
• W2029372231 hasConceptScore W2029372231C159654299 @default.
• W2029372231 hasConceptScore W2029372231C163764329 @default.
• W2029372231 hasConceptScore W2029372231C170286685 @default.
• W2029372231 hasConceptScore W2029372231C203014093 @default.
• W2029372231 hasConceptScore W2029372231C2775915377 @default.
• W2029372231 hasConceptScore W2029372231C2776670291 @default.
• W2029372231 hasConceptScore W2029372231C2776912625 @default.
• W2029372231 hasConceptScore W2029372231C2777077863 @default.
• W2029372231 hasConceptScore W2029372231C2778453870 @default.
• W2029372231 hasConceptScore W2029372231C2778674544 @default.
• W2029372231 hasConceptScore W2029372231C2779075594 @default.
• W2029372231 hasConceptScore W2029372231C2779134260 @default.
• W2029372231 hasConceptScore W2029372231C2779912601 @default.
• W2029372231 hasConceptScore W2029372231C71924100 @default.
• W2029372231 hasConceptScore W2029372231C90924648 @default.

• next