Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029380472> ?p ?o ?g. }
- W2029380472 endingPage "78" @default.
- W2029380472 startingPage "74" @default.
- W2029380472 abstract "Abstract Human monoclonal antibodies are extremely difficult to obtain by hybridoma technology. As an alternative, ‘human‐like’ antibodies have been produced by recombinant DNA technology. The first such engineered antibodies consisted of chimaeric proteins, in which murine variable regions were linked to human constant regions. More recently ‘human’ antibodies have been ‘reshaped’ by transplanting the binding site of a murine antibody into a human antibody. Further‐more antibodies have been dissected into groups of domains (Fab's, Fc's) and for example, Fab's have been joined to enzymes resulting in antibody‐enzyme chimaeras. In addition to their potential clinical applications, engineered antibodies will prove invaluable in studies of structure/function relationships of variable and constant regions." @default.
- W2029380472 created "2016-06-24" @default.
- W2029380472 creator A5012304923 @default.
- W2029380472 creator A5045007040 @default.
- W2029380472 date "1988-02-01" @default.
- W2029380472 modified "2023-10-16" @default.
- W2029380472 title "Engineering of antibodies" @default.
- W2029380472 cites W1579796122 @default.
- W2029380472 cites W1587681168 @default.
- W2029380472 cites W1590194625 @default.
- W2029380472 cites W1598315121 @default.
- W2029380472 cites W1608855442 @default.
- W2029380472 cites W1939186328 @default.
- W2029380472 cites W1970387931 @default.
- W2029380472 cites W1972920532 @default.
- W2029380472 cites W1976232165 @default.
- W2029380472 cites W1980826960 @default.
- W2029380472 cites W1982679430 @default.
- W2029380472 cites W1983494459 @default.
- W2029380472 cites W1986983782 @default.
- W2029380472 cites W1988543833 @default.
- W2029380472 cites W1991512894 @default.
- W2029380472 cites W1994679552 @default.
- W2029380472 cites W1998109852 @default.
- W2029380472 cites W2000727426 @default.
- W2029380472 cites W2002506433 @default.
- W2029380472 cites W2008943399 @default.
- W2029380472 cites W2009230563 @default.
- W2029380472 cites W2014099862 @default.
- W2029380472 cites W2018849234 @default.
- W2029380472 cites W2023095985 @default.
- W2029380472 cites W2030328963 @default.
- W2029380472 cites W2030522563 @default.
- W2029380472 cites W2031545666 @default.
- W2029380472 cites W2033116411 @default.
- W2029380472 cites W2034211674 @default.
- W2029380472 cites W2041140334 @default.
- W2029380472 cites W2047222094 @default.
- W2029380472 cites W2054892173 @default.
- W2029380472 cites W2057058036 @default.
- W2029380472 cites W2057893650 @default.
- W2029380472 cites W2059155938 @default.
- W2029380472 cites W2062638802 @default.
- W2029380472 cites W2063059569 @default.
- W2029380472 cites W2063883448 @default.
- W2029380472 cites W2071979631 @default.
- W2029380472 cites W2073084609 @default.
- W2029380472 cites W2073235310 @default.
- W2029380472 cites W2075097399 @default.
- W2029380472 cites W2082874134 @default.
- W2029380472 cites W2136766474 @default.
- W2029380472 cites W2740745106 @default.
- W2029380472 cites W4253316735 @default.
- W2029380472 cites W47869444 @default.
- W2029380472 doi "https://doi.org/10.1002/bies.950080207" @default.
- W2029380472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3282508" @default.
- W2029380472 hasPublicationYear "1988" @default.
- W2029380472 type Work @default.
- W2029380472 sameAs 2029380472 @default.
- W2029380472 citedByCount "15" @default.
- W2029380472 countsByYear W20293804722016 @default.
- W2029380472 crossrefType "journal-article" @default.
- W2029380472 hasAuthorship W2029380472A5012304923 @default.
- W2029380472 hasAuthorship W2029380472A5045007040 @default.
- W2029380472 hasConcept C104317684 @default.
- W2029380472 hasConcept C147816474 @default.
- W2029380472 hasConcept C153911025 @default.
- W2029380472 hasConcept C159654299 @default.
- W2029380472 hasConcept C181199279 @default.
- W2029380472 hasConcept C203014093 @default.
- W2029380472 hasConcept C2778502174 @default.
- W2029380472 hasConcept C40767141 @default.
- W2029380472 hasConcept C542903549 @default.
- W2029380472 hasConcept C55493867 @default.
- W2029380472 hasConcept C86803240 @default.
- W2029380472 hasConceptScore W2029380472C104317684 @default.
- W2029380472 hasConceptScore W2029380472C147816474 @default.
- W2029380472 hasConceptScore W2029380472C153911025 @default.
- W2029380472 hasConceptScore W2029380472C159654299 @default.
- W2029380472 hasConceptScore W2029380472C181199279 @default.
- W2029380472 hasConceptScore W2029380472C203014093 @default.
- W2029380472 hasConceptScore W2029380472C2778502174 @default.
- W2029380472 hasConceptScore W2029380472C40767141 @default.
- W2029380472 hasConceptScore W2029380472C542903549 @default.
- W2029380472 hasConceptScore W2029380472C55493867 @default.
- W2029380472 hasConceptScore W2029380472C86803240 @default.
- W2029380472 hasIssue "2-3" @default.
- W2029380472 hasLocation W20293804721 @default.
- W2029380472 hasLocation W20293804722 @default.
- W2029380472 hasOpenAccess W2029380472 @default.
- W2029380472 hasPrimaryLocation W20293804721 @default.
- W2029380472 hasRelatedWork W2066367756 @default.
- W2029380472 hasRelatedWork W2343297415 @default.
- W2029380472 hasRelatedWork W2349557033 @default.
- W2029380472 hasRelatedWork W2367313888 @default.
- W2029380472 hasRelatedWork W2368460920 @default.
- W2029380472 hasRelatedWork W2380360044 @default.
- W2029380472 hasRelatedWork W2380817849 @default.