Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029384778> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2029384778 endingPage "299" @default.
- W2029384778 startingPage "291" @default.
- W2029384778 abstract "An analytical method for the determination of lycopene in tissues and plasma of rats is described. The method was validated for the determination of lycopene in liver and plasma with respect to selectivity, linearity, accuracy, recovery and precision. Following precipitation of proteins with water-ethanol plasma was extracted with hexane; tissues were extracted with acetone followed by precipitation of proteins with water-ethanol and extraction of lycopene with hexane. Separation and quantification of geometrical isomers of lycopene was achieved by normal-phase HPLC with UV/VIS detection at 471 nm. The method proved to be selective and specific for lycopene in plasma and liver. Detector response was linear in the range from 2 ng/g to 10 microg/g liver and 0.5 ng/ml to 2 microg/ml plasma, respectively. Average recoveries ranged from 96 to 101% in spiked liver samples and from 91 to 94% in spiked plasma samples. Intra-day variability (C.V.) was < or = 6% and < or = 5% in liver and plasma, respectively. Inter-day precision was < or = 9% for liver samples and < or = 6% for plasma samples. The procedures were successfully applied to the sample analysis of pharmacokinetic and metabolism studies." @default.
- W2029384778 created "2016-06-24" @default.
- W2029384778 creator A5011566050 @default.
- W2029384778 creator A5026241421 @default.
- W2029384778 creator A5068737257 @default.
- W2029384778 creator A5081871766 @default.
- W2029384778 date "2000-03-01" @default.
- W2029384778 modified "2023-10-14" @default.
- W2029384778 title "Determination of lycopene in tissues and plasma of rats by normal-phase high-performance liquid chromatography with photometric detection" @default.
- W2029384778 cites W1921006759 @default.
- W2029384778 cites W1966735916 @default.
- W2029384778 cites W1976594939 @default.
- W2029384778 cites W2012981970 @default.
- W2029384778 cites W2015179981 @default.
- W2029384778 cites W2030237720 @default.
- W2029384778 cites W2076311380 @default.
- W2029384778 cites W2090407376 @default.
- W2029384778 cites W2097787934 @default.
- W2029384778 cites W2142054229 @default.
- W2029384778 cites W2156585356 @default.
- W2029384778 cites W2171691536 @default.
- W2029384778 cites W2176817830 @default.
- W2029384778 cites W2314567402 @default.
- W2029384778 cites W2324658854 @default.
- W2029384778 cites W2333739219 @default.
- W2029384778 doi "https://doi.org/10.1016/s0378-4347(99)00562-9" @default.
- W2029384778 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10755373" @default.
- W2029384778 hasPublicationYear "2000" @default.
- W2029384778 type Work @default.
- W2029384778 sameAs 2029384778 @default.
- W2029384778 citedByCount "20" @default.
- W2029384778 countsByYear W20293847782013 @default.
- W2029384778 countsByYear W20293847782014 @default.
- W2029384778 countsByYear W20293847782015 @default.
- W2029384778 countsByYear W20293847782016 @default.
- W2029384778 countsByYear W20293847782017 @default.
- W2029384778 countsByYear W20293847782019 @default.
- W2029384778 countsByYear W20293847782020 @default.
- W2029384778 countsByYear W20293847782021 @default.
- W2029384778 crossrefType "journal-article" @default.
- W2029384778 hasAuthorship W2029384778A5011566050 @default.
- W2029384778 hasAuthorship W2029384778A5026241421 @default.
- W2029384778 hasAuthorship W2029384778A5068737257 @default.
- W2029384778 hasAuthorship W2029384778A5081871766 @default.
- W2029384778 hasConcept C119128265 @default.
- W2029384778 hasConcept C179998833 @default.
- W2029384778 hasConcept C185592680 @default.
- W2029384778 hasConcept C2777077568 @default.
- W2029384778 hasConcept C2780022147 @default.
- W2029384778 hasConcept C2780161600 @default.
- W2029384778 hasConcept C2781213060 @default.
- W2029384778 hasConcept C28781525 @default.
- W2029384778 hasConcept C43617362 @default.
- W2029384778 hasConcept C4725764 @default.
- W2029384778 hasConcept C55493867 @default.
- W2029384778 hasConcept C74774607 @default.
- W2029384778 hasConcept C95986675 @default.
- W2029384778 hasConceptScore W2029384778C119128265 @default.
- W2029384778 hasConceptScore W2029384778C179998833 @default.
- W2029384778 hasConceptScore W2029384778C185592680 @default.
- W2029384778 hasConceptScore W2029384778C2777077568 @default.
- W2029384778 hasConceptScore W2029384778C2780022147 @default.
- W2029384778 hasConceptScore W2029384778C2780161600 @default.
- W2029384778 hasConceptScore W2029384778C2781213060 @default.
- W2029384778 hasConceptScore W2029384778C28781525 @default.
- W2029384778 hasConceptScore W2029384778C43617362 @default.
- W2029384778 hasConceptScore W2029384778C4725764 @default.
- W2029384778 hasConceptScore W2029384778C55493867 @default.
- W2029384778 hasConceptScore W2029384778C74774607 @default.
- W2029384778 hasConceptScore W2029384778C95986675 @default.
- W2029384778 hasIssue "2" @default.
- W2029384778 hasLocation W20293847781 @default.
- W2029384778 hasLocation W20293847782 @default.
- W2029384778 hasOpenAccess W2029384778 @default.
- W2029384778 hasPrimaryLocation W20293847781 @default.
- W2029384778 hasRelatedWork W1984245414 @default.
- W2029384778 hasRelatedWork W2001243996 @default.
- W2029384778 hasRelatedWork W2027341607 @default.
- W2029384778 hasRelatedWork W2036400894 @default.
- W2029384778 hasRelatedWork W2084062459 @default.
- W2029384778 hasRelatedWork W2096641431 @default.
- W2029384778 hasRelatedWork W2348021725 @default.
- W2029384778 hasRelatedWork W2378635109 @default.
- W2029384778 hasRelatedWork W2379066409 @default.
- W2029384778 hasRelatedWork W2392316154 @default.
- W2029384778 hasVolume "739" @default.
- W2029384778 isParatext "false" @default.
- W2029384778 isRetracted "false" @default.
- W2029384778 magId "2029384778" @default.
- W2029384778 workType "article" @default.