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• W2029386957 abstract "We have analyzed the relationship between the development of transplant-related coronary artery disease (TRCAD) and the following potential risk factors: (a). number of HLA mismatches between recipient and donor; (b). production of anti-HLA antibodies; (c). growth of lymphocytes infiltrating the graft; and (d). frequency of biopsy proven episodes of acute rejection. The study population consisted of 285 adult heart allograft recipients who were monitored over a period of two years or more. The results demonstrate a significant correlation between TRCAD, generation of anti-HLA class II antibodies and potential of lymphocytes infiltrating the graft to proliferate ex-vivo in medium containing IL-2. Humoral and cellular immune responses to HLA-DR antigens expressed by the graft seem to underlie the development of TRCAD." @default.
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• W2029386957 date "2004-01-01" @default.
• W2029386957 modified "2023-10-16" @default.
• W2029386957 title "Anti-HLA antibodies in heart transplantation" @default.
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• W2029386957 doi "https://doi.org/10.1016/j.trim.2003.08.002" @default.
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