FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029387532> ?p ?o ?g. }

• W2029387532 endingPage "615" @default.
• W2029387532 startingPage "605" @default.
• W2029387532 abstract "Polyimide regenerative electrodes (RE) constitute a promising neural interface to selectively stimulate regenerating fibers in injured nerves. The characteristics of the regeneration through an implanted RE, however, are only beginning to be established. It was recently shown that the number of myelinated fibers distal to the implant reached control values 7 months postimplant; however, the functional recovery remained substantially below normal [J Biomed Mater Res 60 (2002) 517]. In this study we sought to determine the magnitude, and possible selectivity, of axonal regeneration through the RE by counting sensory and motor neurons that were retrogradely labeled from double tracer deposits in the sciatic nerve. Adult rats had their right sciatic nerves transected, and the stumps were placed in silicone tubes; some simply were filled with saline (Tube group), and others held a RE in its center (RE group). Simultaneously, the proximal stump was exposed to Diamidino Yellow. Two months later the nerves were bilaterally excised distal to the implant, and exposed to Fast Blue. Electrophysiological recordings, and skin nociceptive responses confirmed previous findings of partial functional recovery. In controls, an average of 20,000 and 3080 neurons were labeled in L4–L5 dorsal root ganglia (with minor contributions from L3 and/or L6), and in the ventral horn of the lumbar spinal cord, respectively. In the regenerating side, 35% of the DRG neurons were double-labeled, without differences between groups. In contrast, only 7.5% of motoneurons were double-labeled in the RE group, vs. 21% in the Tube group. Moreover, smaller ganglion cells regenerated better than large neurons by a significant 13.8%. These results indicate that the RE is not an obstacle for the re-growth of sensory fibers, but partially hinders fiber regeneration from motoneurons. They also suggest that fine fibers may be at an advantage over large ones to regenerate through the RE." @default.
• W2029387532 created "2016-06-24" @default.
• W2029387532 creator A5028471102 @default.
• W2029387532 creator A5041871611 @default.
• W2029387532 creator A5050271380 @default.
• W2029387532 creator A5064076690 @default.
• W2029387532 creator A5080751235 @default.
• W2029387532 date "2004-01-01" @default.
• W2029387532 modified "2023-10-09" @default.
• W2029387532 title "Differential growth of axons from sensory and motor neurons through a regenerative electrode: A stereological, retrograde tracer, and functional study in the rat" @default.
• W2029387532 cites W1551323478 @default.
• W2029387532 cites W1874125315 @default.
• W2029387532 cites W1966103731 @default.
• W2029387532 cites W1967780935 @default.
• W2029387532 cites W1968759033 @default.
• W2029387532 cites W1973501593 @default.
• W2029387532 cites W1974858539 @default.
• W2029387532 cites W1983776987 @default.
• W2029387532 cites W1984325684 @default.
• W2029387532 cites W2005466239 @default.
• W2029387532 cites W2006607961 @default.
• W2029387532 cites W2010021349 @default.
• W2029387532 cites W2014895403 @default.
• W2029387532 cites W2020165673 @default.
• W2029387532 cites W2023131407 @default.
• W2029387532 cites W2033812657 @default.
• W2029387532 cites W2037367554 @default.
• W2029387532 cites W2039400081 @default.
• W2029387532 cites W2046557041 @default.
• W2029387532 cites W2051753303 @default.
• W2029387532 cites W2051922464 @default.
• W2029387532 cites W2053517954 @default.
• W2029387532 cites W2055114377 @default.
• W2029387532 cites W2072571580 @default.
• W2029387532 cites W2079958431 @default.
• W2029387532 cites W2082784433 @default.
• W2029387532 cites W2084552832 @default.
• W2029387532 cites W2084966640 @default.
• W2029387532 cites W2089527008 @default.
• W2029387532 cites W2097796725 @default.
• W2029387532 cites W2102823461 @default.
• W2029387532 cites W2105382539 @default.
• W2029387532 cites W2111405228 @default.
• W2029387532 cites W2111686057 @default.
• W2029387532 cites W2116103812 @default.
• W2029387532 cites W2120396832 @default.
• W2029387532 cites W2124792768 @default.
• W2029387532 cites W2145630514 @default.
• W2029387532 cites W2149921519 @default.
• W2029387532 doi "https://doi.org/10.1016/j.neuroscience.2004.07.017" @default.
• W2029387532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15381289" @default.
• W2029387532 hasPublicationYear "2004" @default.
• W2029387532 type Work @default.
• W2029387532 sameAs 2029387532 @default.
• W2029387532 citedByCount "45" @default.
• W2029387532 countsByYear W20293875322012 @default.
• W2029387532 countsByYear W20293875322013 @default.
• W2029387532 countsByYear W20293875322014 @default.
• W2029387532 countsByYear W20293875322015 @default.
• W2029387532 countsByYear W20293875322016 @default.
• W2029387532 countsByYear W20293875322017 @default.
• W2029387532 countsByYear W20293875322018 @default.
• W2029387532 countsByYear W20293875322020 @default.
• W2029387532 countsByYear W20293875322021 @default.
• W2029387532 countsByYear W20293875322022 @default.
• W2029387532 countsByYear W20293875322023 @default.
• W2029387532 crossrefType "journal-article" @default.
• W2029387532 hasAuthorship W2029387532A5028471102 @default.
• W2029387532 hasAuthorship W2029387532A5041871611 @default.
• W2029387532 hasAuthorship W2029387532A5050271380 @default.
• W2029387532 hasAuthorship W2029387532A5064076690 @default.
• W2029387532 hasAuthorship W2029387532A5080751235 @default.
• W2029387532 hasConcept C105702510 @default.
• W2029387532 hasConcept C141071460 @default.
• W2029387532 hasConcept C169760540 @default.
• W2029387532 hasConcept C171056886 @default.
• W2029387532 hasConcept C185263204 @default.
• W2029387532 hasConcept C185592680 @default.
• W2029387532 hasConcept C2776281502 @default.
• W2029387532 hasConcept C2780775167 @default.
• W2029387532 hasConcept C2781149210 @default.
• W2029387532 hasConcept C2781411149 @default.
• W2029387532 hasConcept C71924100 @default.
• W2029387532 hasConcept C86803240 @default.
• W2029387532 hasConcept C94487597 @default.
• W2029387532 hasConcept C95444343 @default.
• W2029387532 hasConceptScore W2029387532C105702510 @default.
• W2029387532 hasConceptScore W2029387532C141071460 @default.
• W2029387532 hasConceptScore W2029387532C169760540 @default.
• W2029387532 hasConceptScore W2029387532C171056886 @default.
• W2029387532 hasConceptScore W2029387532C185263204 @default.
• W2029387532 hasConceptScore W2029387532C185592680 @default.
• W2029387532 hasConceptScore W2029387532C2776281502 @default.
• W2029387532 hasConceptScore W2029387532C2780775167 @default.
• W2029387532 hasConceptScore W2029387532C2781149210 @default.
• W2029387532 hasConceptScore W2029387532C2781411149 @default.
• W2029387532 hasConceptScore W2029387532C71924100 @default.
• W2029387532 hasConceptScore W2029387532C86803240 @default.

• next