Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029412262> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2029412262 endingPage "725" @default.
- W2029412262 startingPage "719" @default.
- W2029412262 abstract "Fluorine-18 labeled analog of D-fructose, 1-deoxy-1-[18F]fluoro-D- fructose (1-[18F]FDFrc), was synthesized by nucleophilic substitution of [18F]fluoride ion and the effect of the fluorine substitution on its in vivo metabolism was investigated. The tissue distributions of 1-[18F]FDFrc in rats and tumor bearing mice showed initial high uptake and subsequent rapid washout of the radioactivity in the principal sites of D-fructose metabolism (kidneys, liver and small intestine). The uptakes in the brain and tumor (fibrosarcoma) were the lowest and moderate, respectively, but tended to increase with time. The in vivo metabolic studies of 1-[18F]FDFrc and nonradioactive 1-FDFrc in mouse brain and tumor showed that the fluorinated analog remained unmetabolized in these tissues, indicating that the substitution of fluorine at the C-1 position produces a nonmetabolizable analog of D-fructose. Thus, 1-[18F]FDFrc had no features of a metabolic trapping tracer without showing any appreciable organ or tumor specific localization." @default.
- W2029412262 created "2016-06-24" @default.
- W2029412262 creator A5018065277 @default.
- W2029412262 creator A5025453239 @default.
- W2029412262 creator A5045802956 @default.
- W2029412262 creator A5053226621 @default.
- W2029412262 creator A5087175752 @default.
- W2029412262 creator A5090482384 @default.
- W2029412262 date "1995-08-01" @default.
- W2029412262 modified "2023-10-11" @default.
- W2029412262 title "Radiosynthesis, rodent biodistribution, and metabolism of 1-deoxy-1-[18F]fluoro-d-fructose" @default.
- W2029412262 cites W1585621665 @default.
- W2029412262 cites W16603568 @default.
- W2029412262 cites W1835906180 @default.
- W2029412262 cites W1973730404 @default.
- W2029412262 cites W1977311571 @default.
- W2029412262 cites W1984371787 @default.
- W2029412262 cites W1990695593 @default.
- W2029412262 cites W2020987495 @default.
- W2029412262 cites W2024464162 @default.
- W2029412262 cites W2072451938 @default.
- W2029412262 cites W2079063981 @default.
- W2029412262 cites W2336962986 @default.
- W2029412262 cites W2883729545 @default.
- W2029412262 cites W3004511368 @default.
- W2029412262 doi "https://doi.org/10.1016/0969-8051(95)00018-s" @default.
- W2029412262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8535332" @default.
- W2029412262 hasPublicationYear "1995" @default.
- W2029412262 type Work @default.
- W2029412262 sameAs 2029412262 @default.
- W2029412262 citedByCount "19" @default.
- W2029412262 countsByYear W20294122622012 @default.
- W2029412262 countsByYear W20294122622013 @default.
- W2029412262 countsByYear W20294122622017 @default.
- W2029412262 countsByYear W20294122622020 @default.
- W2029412262 countsByYear W20294122622022 @default.
- W2029412262 countsByYear W20294122622023 @default.
- W2029412262 crossrefType "journal-article" @default.
- W2029412262 hasAuthorship W2029412262A5018065277 @default.
- W2029412262 hasAuthorship W2029412262A5025453239 @default.
- W2029412262 hasAuthorship W2029412262A5045802956 @default.
- W2029412262 hasAuthorship W2029412262A5053226621 @default.
- W2029412262 hasAuthorship W2029412262A5087175752 @default.
- W2029412262 hasAuthorship W2029412262A5090482384 @default.
- W2029412262 hasConcept C150903083 @default.
- W2029412262 hasConcept C177322064 @default.
- W2029412262 hasConcept C185592680 @default.
- W2029412262 hasConcept C202751555 @default.
- W2029412262 hasConcept C207001950 @default.
- W2029412262 hasConcept C2776970183 @default.
- W2029412262 hasConcept C2776970464 @default.
- W2029412262 hasConcept C2777807558 @default.
- W2029412262 hasConcept C55493867 @default.
- W2029412262 hasConcept C62231903 @default.
- W2029412262 hasConcept C86803240 @default.
- W2029412262 hasConceptScore W2029412262C150903083 @default.
- W2029412262 hasConceptScore W2029412262C177322064 @default.
- W2029412262 hasConceptScore W2029412262C185592680 @default.
- W2029412262 hasConceptScore W2029412262C202751555 @default.
- W2029412262 hasConceptScore W2029412262C207001950 @default.
- W2029412262 hasConceptScore W2029412262C2776970183 @default.
- W2029412262 hasConceptScore W2029412262C2776970464 @default.
- W2029412262 hasConceptScore W2029412262C2777807558 @default.
- W2029412262 hasConceptScore W2029412262C55493867 @default.
- W2029412262 hasConceptScore W2029412262C62231903 @default.
- W2029412262 hasConceptScore W2029412262C86803240 @default.
- W2029412262 hasFunder F4320320912 @default.
- W2029412262 hasIssue "6" @default.
- W2029412262 hasLocation W20294122621 @default.
- W2029412262 hasLocation W20294122622 @default.
- W2029412262 hasOpenAccess W2029412262 @default.
- W2029412262 hasPrimaryLocation W20294122621 @default.
- W2029412262 hasRelatedWork W128904834 @default.
- W2029412262 hasRelatedWork W1993687774 @default.
- W2029412262 hasRelatedWork W2016537668 @default.
- W2029412262 hasRelatedWork W2045191886 @default.
- W2029412262 hasRelatedWork W2606102757 @default.
- W2029412262 hasRelatedWork W2884199215 @default.
- W2029412262 hasRelatedWork W3016588559 @default.
- W2029412262 hasRelatedWork W3091847708 @default.
- W2029412262 hasRelatedWork W4377028737 @default.
- W2029412262 hasRelatedWork W4384524295 @default.
- W2029412262 hasVolume "22" @default.
- W2029412262 isParatext "false" @default.
- W2029412262 isRetracted "false" @default.
- W2029412262 magId "2029412262" @default.
- W2029412262 workType "article" @default.