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• W2029421925 abstract "Quercetin is an effective inhibitor of human myeloperoxidase (MPO) activity, both with purified enzyme (IC50=3.5 μM) and in a system using stimulated human neutrophils. Quercetin is significantly more potent than three other related compounds (rutin, rutin sulfate and troxerutin) and than methimazole, a previously-known myeloperoxidase inhibitor. The inhibitory activity of quercetin is of the competitive type. Moreover, quercetin is directly able to scavenge hypochlorous acid (HOCl), a chlorinated species generated by the, MPO/H2O2/Cl− system." @default.
• W2029421925 created "2016-06-24" @default.
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• W2029421925 date "1988-05-01" @default.
• W2029421925 modified "2023-10-15" @default.
• W2029421925 title "Human myeloperoxidase activity is inhibited in vitro by quercetin. Comparison with three related compounds" @default.
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• W2029421925 doi "https://doi.org/10.1007/bf01940544" @default.
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