FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029440786> ?p ?o ?g. }

• W2029440786 endingPage "816" @default.
• W2029440786 startingPage "812" @default.
• W2029440786 abstract "Background: Traditional biomarkers for heavy alcohol use include serum carbohydrate-deficient transferrin (CDT), the enzymes aspartate aminotranserase (AST), and alanine aminotransferase (ALT) as well as gamma-glutamyl transferase (GGT). Measurement of the nonoxidative ethanol metabolite, ethyl glucuronide (EtG) in hair, has been proposed as a new marker with superior qualities. The aim of this study was to investigate the sensitivity of EtG in hair to detect heavy alcohol use compared with CDT, AST, ALT, and GGT. We also wanted to study the quantitative relation between alcohol intake and the different biomarkers. Methods: Sixteen patients with a history of heavy alcohol use over the previous 3 months were recruited directly after admission to a withdrawal clinic. They were thoroughly interviewed about their drinking pattern as well as relevant diseases and use of medicines or drugs. Serum was sampled and analyzed for %CDT, AST, ALT, and GGT. Hair samples were collected and analyzed for EtG. Results: The mean estimated daily intake (EDI) over the previous 3 months was 206 ± 136 g pure alcohol. All patients fulfilled the criteria for heavy alcohol use. The sensitivity to detect heavy alcohol use was 64% for %CDT, 67% for AST, 67% for ALT, 93% for GGT, and 94% for EtG. There was no correlation between the quantitative values of EDI and %CDT, AST, ALT, and GGT. There was a positive, statistically significant correlation between EDI and the level of EtG in hair. Conclusions: In this study, EtG in hair and GGT showed the best sensitivity to detect heavy alcohol use and there was a positive correlation between EDI and the concentrations of EtG in hair. Before giving recommendations for clinical practice, further studies should be carried out on larger materials and populations with a wider range of alcohol intake." @default.
• W2029440786 created "2016-06-24" @default.
• W2029440786 creator A5032511191 @default.
• W2029440786 creator A5062686223 @default.
• W2029440786 creator A5069261558 @default.
• W2029440786 creator A5082802008 @default.
• W2029440786 creator A5089171283 @default.
• W2029440786 date "2009-05-01" @default.
• W2029440786 modified "2023-10-03" @default.
• W2029440786 title "Ethyl Glucuronide in Hair Compared With Traditional Alcohol Biomarkers-A Pilot Study of Heavy Drinkers Referred to an Alcohol Detoxification Unit" @default.
• W2029440786 cites W1542102459 @default.
• W2029440786 cites W1964320518 @default.
• W2029440786 cites W1965182927 @default.
• W2029440786 cites W1983649331 @default.
• W2029440786 cites W1984207951 @default.
• W2029440786 cites W1987860779 @default.
• W2029440786 cites W1992238547 @default.
• W2029440786 cites W1999269123 @default.
• W2029440786 cites W2008393745 @default.
• W2029440786 cites W2010403810 @default.
• W2029440786 cites W2014113596 @default.
• W2029440786 cites W2018900157 @default.
• W2029440786 cites W2019126388 @default.
• W2029440786 cites W2024494902 @default.
• W2029440786 cites W2033923891 @default.
• W2029440786 cites W2038942607 @default.
• W2029440786 cites W2052723208 @default.
• W2029440786 cites W2060947228 @default.
• W2029440786 cites W2076568298 @default.
• W2029440786 cites W2077960177 @default.
• W2029440786 cites W2090332890 @default.
• W2029440786 cites W2092059151 @default.
• W2029440786 cites W2094664659 @default.
• W2029440786 cites W2101698063 @default.
• W2029440786 cites W2102266405 @default.
• W2029440786 cites W2117251309 @default.
• W2029440786 cites W2123479244 @default.
• W2029440786 cites W2134528230 @default.
• W2029440786 cites W2136526319 @default.
• W2029440786 cites W2145052205 @default.
• W2029440786 cites W2150125017 @default.
• W2029440786 cites W4328001250 @default.
• W2029440786 cites W59176708 @default.
• W2029440786 doi "https://doi.org/10.1111/j.1530-0277.2009.00900.x" @default.
• W2029440786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19298326" @default.
• W2029440786 hasPublicationYear "2009" @default.
• W2029440786 type Work @default.
• W2029440786 sameAs 2029440786 @default.
• W2029440786 citedByCount "51" @default.
• W2029440786 countsByYear W20294407862012 @default.
• W2029440786 countsByYear W20294407862013 @default.
• W2029440786 countsByYear W20294407862014 @default.
• W2029440786 countsByYear W20294407862015 @default.
• W2029440786 countsByYear W20294407862016 @default.
• W2029440786 countsByYear W20294407862018 @default.
• W2029440786 countsByYear W20294407862019 @default.
• W2029440786 countsByYear W20294407862021 @default.
• W2029440786 countsByYear W20294407862022 @default.
• W2029440786 countsByYear W20294407862023 @default.
• W2029440786 crossrefType "journal-article" @default.
• W2029440786 hasAuthorship W2029440786A5032511191 @default.
• W2029440786 hasAuthorship W2029440786A5062686223 @default.
• W2029440786 hasAuthorship W2029440786A5069261558 @default.
• W2029440786 hasAuthorship W2029440786A5082802008 @default.
• W2029440786 hasAuthorship W2029440786A5089171283 @default.
• W2029440786 hasConcept C126322002 @default.
• W2029440786 hasConcept C181199279 @default.
• W2029440786 hasConcept C185592680 @default.
• W2029440786 hasConcept C2777477808 @default.
• W2029440786 hasConcept C2778248655 @default.
• W2029440786 hasConcept C2778606649 @default.
• W2029440786 hasConcept C2780161600 @default.
• W2029440786 hasConcept C2780740339 @default.
• W2029440786 hasConcept C2781066024 @default.
• W2029440786 hasConcept C2781278919 @default.
• W2029440786 hasConcept C3018430727 @default.
• W2029440786 hasConcept C3019635848 @default.
• W2029440786 hasConcept C42407357 @default.
• W2029440786 hasConcept C55493867 @default.
• W2029440786 hasConcept C71924100 @default.
• W2029440786 hasConcept C90924648 @default.
• W2029440786 hasConceptScore W2029440786C126322002 @default.
• W2029440786 hasConceptScore W2029440786C181199279 @default.
• W2029440786 hasConceptScore W2029440786C185592680 @default.
• W2029440786 hasConceptScore W2029440786C2777477808 @default.
• W2029440786 hasConceptScore W2029440786C2778248655 @default.
• W2029440786 hasConceptScore W2029440786C2778606649 @default.
• W2029440786 hasConceptScore W2029440786C2780161600 @default.
• W2029440786 hasConceptScore W2029440786C2780740339 @default.
• W2029440786 hasConceptScore W2029440786C2781066024 @default.
• W2029440786 hasConceptScore W2029440786C2781278919 @default.
• W2029440786 hasConceptScore W2029440786C3018430727 @default.
• W2029440786 hasConceptScore W2029440786C3019635848 @default.
• W2029440786 hasConceptScore W2029440786C42407357 @default.
• W2029440786 hasConceptScore W2029440786C55493867 @default.
• W2029440786 hasConceptScore W2029440786C71924100 @default.
• W2029440786 hasConceptScore W2029440786C90924648 @default.
• W2029440786 hasIssue "5" @default.

• next