FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029454447> ?p ?o ?g. }

• W2029454447 endingPage "1249" @default.
• W2029454447 startingPage "1243" @default.
• W2029454447 abstract "In the United States, composites accounted for nearly 70% of the 173.2 million composite and amalgam restorations placed in 2006 (Kingman et al., 2012), and it is likely that the use of composite will continue to increase as dentists phase out dental amalgam. This trend is not, however, without consequences. The failure rate of composite restorations is double that of amalgam (Ferracane, 2013). Composite restorations accumulate more biofilm, experience more secondary decay, and require more frequent replacement. In vivo biodegradation of the adhesive bond at the composite-tooth interface is a major contributor to the cascade of events leading to restoration failure. Binding by proteins, particularly gp340, from the salivary pellicle leads to biofilm attachment, which accelerates degradation of the interfacial bond and demineralization of the tooth by recruiting the pioneer bacterium Streptococcus mutans to the surface. Bacterial production of lactic acid lowers the pH of the oral microenvironment, erodes hydroxyapatite in enamel and dentin, and promotes hydrolysis of the adhesive. Secreted esterases further hydrolyze the adhesive polymer, exposing the soft underlying collagenous dentinal matrix and allowing further infiltration by the pathogenic biofilm. Manifold approaches are being pursued to increase the longevity of composite dental restorations based on the major contributing factors responsible for degradation. The key material and biological components and the interactions involved in the destructive processes, including recent advances in understanding the structural and molecular basis of biofilm recruitment, are described in this review. Innovative strategies to mitigate these pathogenic effects and slow deterioration are discussed." @default.
• W2029454447 created "2016-06-24" @default.
• W2029454447 creator A5004539283 @default.
• W2029454447 creator A5017997193 @default.
• W2029454447 creator A5044702300 @default.
• W2029454447 creator A5068700742 @default.
• W2029454447 creator A5074781546 @default.
• W2029454447 date "2014-09-04" @default.
• W2029454447 modified "2023-10-06" @default.
• W2029454447 title "Proteins, Pathogens, and Failure at the Composite-Tooth Interface" @default.
• W2029454447 cites W1495302892 @default.
• W2029454447 cites W1696742755 @default.
• W2029454447 cites W1916961071 @default.
• W2029454447 cites W1965018428 @default.
• W2029454447 cites W1968040337 @default.
• W2029454447 cites W1971480083 @default.
• W2029454447 cites W1971583779 @default.
• W2029454447 cites W1975793715 @default.
• W2029454447 cites W1978174631 @default.
• W2029454447 cites W1987702644 @default.
• W2029454447 cites W2001954050 @default.
• W2029454447 cites W2010534026 @default.
• W2029454447 cites W2026912384 @default.
• W2029454447 cites W2028243400 @default.
• W2029454447 cites W2029535061 @default.
• W2029454447 cites W2033628063 @default.
• W2029454447 cites W2036132117 @default.
• W2029454447 cites W2037163710 @default.
• W2029454447 cites W2040040304 @default.
• W2029454447 cites W2042784583 @default.
• W2029454447 cites W2047881138 @default.
• W2029454447 cites W2051545426 @default.
• W2029454447 cites W2056583753 @default.
• W2029454447 cites W2069773606 @default.
• W2029454447 cites W2073761677 @default.
• W2029454447 cites W2079193522 @default.
• W2029454447 cites W2090881476 @default.
• W2029454447 cites W2091132707 @default.
• W2029454447 cites W2098976315 @default.
• W2029454447 cites W2099124088 @default.
• W2029454447 cites W2104296371 @default.
• W2029454447 cites W2107713471 @default.
• W2029454447 cites W2109523987 @default.
• W2029454447 cites W2111535845 @default.
• W2029454447 cites W2115460487 @default.
• W2029454447 cites W2117358266 @default.
• W2029454447 cites W2118293741 @default.
• W2029454447 cites W2123791769 @default.
• W2029454447 cites W2130458666 @default.
• W2029454447 cites W2131314048 @default.
• W2029454447 cites W2133640250 @default.
• W2029454447 cites W2135724989 @default.
• W2029454447 cites W2139778157 @default.
• W2029454447 cites W2141065279 @default.
• W2029454447 cites W2144618094 @default.
• W2029454447 cites W2156243205 @default.
• W2029454447 cites W2162388061 @default.
• W2029454447 cites W2162485341 @default.
• W2029454447 cites W2168373863 @default.
• W2029454447 cites W2168543691 @default.
• W2029454447 cites W2170906176 @default.
• W2029454447 cites W2322289455 @default.
• W2029454447 cites W2335530470 @default.
• W2029454447 doi "https://doi.org/10.1177/0022034514550039" @default.
• W2029454447 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4237635" @default.
• W2029454447 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25190266" @default.
• W2029454447 hasPublicationYear "2014" @default.
• W2029454447 type Work @default.
• W2029454447 sameAs 2029454447 @default.
• W2029454447 citedByCount "111" @default.
• W2029454447 countsByYear W20294544472015 @default.
• W2029454447 countsByYear W20294544472016 @default.
• W2029454447 countsByYear W20294544472017 @default.
• W2029454447 countsByYear W20294544472018 @default.
• W2029454447 countsByYear W20294544472019 @default.
• W2029454447 countsByYear W20294544472020 @default.
• W2029454447 countsByYear W20294544472021 @default.
• W2029454447 countsByYear W20294544472022 @default.
• W2029454447 countsByYear W20294544472023 @default.
• W2029454447 crossrefType "journal-article" @default.
• W2029454447 hasAuthorship W2029454447A5004539283 @default.
• W2029454447 hasAuthorship W2029454447A5017997193 @default.
• W2029454447 hasAuthorship W2029454447A5044702300 @default.
• W2029454447 hasAuthorship W2029454447A5068700742 @default.
• W2029454447 hasAuthorship W2029454447A5074781546 @default.
• W2029454447 hasBestOaLocation W20294544472 @default.
• W2029454447 hasConcept C104779481 @default.
• W2029454447 hasConcept C147789679 @default.
• W2029454447 hasConcept C156887251 @default.
• W2029454447 hasConcept C159985019 @default.
• W2029454447 hasConcept C17525397 @default.
• W2029454447 hasConcept C185592680 @default.
• W2029454447 hasConcept C192562407 @default.
• W2029454447 hasConcept C199343813 @default.
• W2029454447 hasConcept C2776052348 @default.
• W2029454447 hasConcept C2778430296 @default.
• W2029454447 hasConcept C2779227376 @default.
• W2029454447 hasConcept C2779263046 @default.

• next