FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029454804> ?p ?o ?g. }

• W2029454804 endingPage "178" @default.
• W2029454804 startingPage "173" @default.
• W2029454804 abstract "A high surface density of the openings of the surface connected canalicular system (SCCS) has been observed in the freeze-fractured plasma membrane of circulating platelets in rabbits fed an atherogenic diet and in hypercholesterolemic type IIa patients. In vitro tests have revealed a correlation between the increased surface density of the SCCS openings and the initial steps of platelet activation. 8-Chlorocarbochromen, a new drug which enhances the in vivo release of prostacyclin from the arterial wall, has been found to be effective in reducing the high surface density of SCCS openings in platelets of rabbits on an atherogenic diet. The present study shows that circulating platelets from patients with peripheral vascular disease present a high surface density of SCCS openings compared to that observed in control subjects. After a single oral administration of 8-chlorocarbochromen, a reduction of the high number of these openings has been observed. Likewise, beta-thromboglobulin levels were found to be high in the patients and to be significantly reduced after oral administration of the drug. This study shows ultrastructural modifications of platelets in conditions related to atherosclerosis and includes data on the effectiveness of 8-chlorocarbochromen in reducing the platelet activation of these patients." @default.
• W2029454804 created "2016-06-24" @default.
• W2029454804 creator A5008740441 @default.
• W2029454804 creator A5011762682 @default.
• W2029454804 creator A5023642245 @default.
• W2029454804 creator A5030520654 @default.
• W2029454804 creator A5036185912 @default.
• W2029454804 creator A5051577220 @default.
• W2029454804 creator A5079120040 @default.
• W2029454804 date "1986-11-01" @default.
• W2029454804 modified "2023-10-18" @default.
• W2029454804 title "Ultrastructural modifications of the platelet plasma membrane in vascular diseases and the effect of a carbochromen derivative as studied by freeze-fracture and computer measurement" @default.
• W2029454804 cites W1985856451 @default.
• W2029454804 cites W1997524000 @default.
• W2029454804 cites W2029466610 @default.
• W2029454804 cites W2032596143 @default.
• W2029454804 cites W2034783985 @default.
• W2029454804 cites W2051322044 @default.
• W2029454804 cites W2051328470 @default.
• W2029454804 cites W2061755142 @default.
• W2029454804 cites W2068476210 @default.
• W2029454804 cites W2070635537 @default.
• W2029454804 cites W2418742295 @default.
• W2029454804 cites W2434803986 @default.
• W2029454804 cites W2787926097 @default.
• W2029454804 cites W2789927847 @default.
• W2029454804 cites W2793293321 @default.
• W2029454804 cites W3023642540 @default.
• W2029454804 cites W45316589 @default.
• W2029454804 cites W2394858131 @default.
• W2029454804 doi "https://doi.org/10.1016/0021-9150(86)90064-x" @default.
• W2029454804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2948512" @default.
• W2029454804 hasPublicationYear "1986" @default.
• W2029454804 type Work @default.
• W2029454804 sameAs 2029454804 @default.
• W2029454804 citedByCount "6" @default.
• W2029454804 countsByYear W20294548042015 @default.
• W2029454804 countsByYear W20294548042022 @default.
• W2029454804 crossrefType "journal-article" @default.
• W2029454804 hasAuthorship W2029454804A5008740441 @default.
• W2029454804 hasAuthorship W2029454804A5011762682 @default.
• W2029454804 hasAuthorship W2029454804A5023642245 @default.
• W2029454804 hasAuthorship W2029454804A5030520654 @default.
• W2029454804 hasAuthorship W2029454804A5036185912 @default.
• W2029454804 hasAuthorship W2029454804A5051577220 @default.
• W2029454804 hasAuthorship W2029454804A5079120040 @default.
• W2029454804 hasConcept C12554922 @default.
• W2029454804 hasConcept C126322002 @default.
• W2029454804 hasConcept C134018914 @default.
• W2029454804 hasConcept C142724271 @default.
• W2029454804 hasConcept C150903083 @default.
• W2029454804 hasConcept C185592680 @default.
• W2029454804 hasConcept C202751555 @default.
• W2029454804 hasConcept C207001950 @default.
• W2029454804 hasConcept C2777056448 @default.
• W2029454804 hasConcept C2780076745 @default.
• W2029454804 hasConcept C2781128415 @default.
• W2029454804 hasConcept C3018697912 @default.
• W2029454804 hasConcept C3020090656 @default.
• W2029454804 hasConcept C46762472 @default.
• W2029454804 hasConcept C55493867 @default.
• W2029454804 hasConcept C71924100 @default.
• W2029454804 hasConcept C86803240 @default.
• W2029454804 hasConcept C87555872 @default.
• W2029454804 hasConcept C89560881 @default.
• W2029454804 hasConcept C98274493 @default.
• W2029454804 hasConceptScore W2029454804C12554922 @default.
• W2029454804 hasConceptScore W2029454804C126322002 @default.
• W2029454804 hasConceptScore W2029454804C134018914 @default.
• W2029454804 hasConceptScore W2029454804C142724271 @default.
• W2029454804 hasConceptScore W2029454804C150903083 @default.
• W2029454804 hasConceptScore W2029454804C185592680 @default.
• W2029454804 hasConceptScore W2029454804C202751555 @default.
• W2029454804 hasConceptScore W2029454804C207001950 @default.
• W2029454804 hasConceptScore W2029454804C2777056448 @default.
• W2029454804 hasConceptScore W2029454804C2780076745 @default.
• W2029454804 hasConceptScore W2029454804C2781128415 @default.
• W2029454804 hasConceptScore W2029454804C3018697912 @default.
• W2029454804 hasConceptScore W2029454804C3020090656 @default.
• W2029454804 hasConceptScore W2029454804C46762472 @default.
• W2029454804 hasConceptScore W2029454804C55493867 @default.
• W2029454804 hasConceptScore W2029454804C71924100 @default.
• W2029454804 hasConceptScore W2029454804C86803240 @default.
• W2029454804 hasConceptScore W2029454804C87555872 @default.
• W2029454804 hasConceptScore W2029454804C89560881 @default.
• W2029454804 hasConceptScore W2029454804C98274493 @default.
• W2029454804 hasIssue "2" @default.
• W2029454804 hasLocation W20294548041 @default.
• W2029454804 hasLocation W20294548042 @default.
• W2029454804 hasOpenAccess W2029454804 @default.
• W2029454804 hasPrimaryLocation W20294548041 @default.
• W2029454804 hasRelatedWork W196136822 @default.
• W2029454804 hasRelatedWork W2029454804 @default.
• W2029454804 hasRelatedWork W2043719604 @default.
• W2029454804 hasRelatedWork W2070852875 @default.
• W2029454804 hasRelatedWork W2091233247 @default.
• W2029454804 hasRelatedWork W2164722961 @default.
• W2029454804 hasRelatedWork W2409324618 @default.

• next