FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W202947524> ?p ?o ?g. }

• W202947524 endingPage "343" @default.
• W202947524 startingPage "338" @default.
• W202947524 abstract "Vitamin E serves an important role in protecting the cellular membrane constituents from peroxidative damage. Biochemical and functional studies were performed on polymorphonuclear leukocytes (PMN) from vitamin-E deficient and control rats to investigate the consequences of uncontrolled peroxidation of the rat PMN membrane. Rats fed a vitamin-E-doficient diet for 2 mo had serum tocopherol levels of only 5.1% of control and exhibited a twofold increase in membrane polyunsaturated fatty acid (PUFA) peroxidation as measured by malonaldehyde production. As a consequence of vitamin-E deficiency, chemotaxis in response to bacterial culture filtrate was deficient. Ingestion was also impaired when saturating concentrations of IgG- and C3b-coated and unopsonized albumin-coated paraffin oil droplets were employed, and ingestion remained deficient when performed in an anaerobic environment. The altered chemotaxis and ingestion in the deficient PMN were restored to normal by 18 hr following the parenteral administration of vitamin E. The deficient PMN ingested and killed C3b-coated Staphylococcus aureus 502-A normally when the bacteria-to-cell ratio was no more than 10:1. Oxygen consumption and hydrogen peroxide release were enhanced in the phagocytosing vitamin-E-deficient PMN. Depletion of vitamin E did not lead to impairment of adherence, surface polarization of concanavalin A into caps, or lysosomal enzyme release. These latter functions are subserved by glutathione-responsive microtubules as well as by actomyosin-containing microfilaments. Thus, the consequences of vitamin-E deficiency in PMN were selective to those areas of the membrane involved in triggering chemotactic, ingestive, and oxidative responses." @default.
• W202947524 created "2016-06-24" @default.
• W202947524 creator A5008970027 @default.
• W202947524 creator A5024968001 @default.
• W202947524 creator A5088809773 @default.
• W202947524 date "1980-02-01" @default.
• W202947524 modified "2023-09-27" @default.
• W202947524 title "Consequences of vitamin-E deficiency on the phagocytic and oxidative functions of the rat polymorphonuclear leukocyte" @default.
• W202947524 cites W1530859280 @default.
• W202947524 cites W1541881494 @default.
• W202947524 cites W1957020011 @default.
• W202947524 cites W1965809927 @default.
• W202947524 cites W1972936152 @default.
• W202947524 cites W1978502718 @default.
• W202947524 cites W1989908548 @default.
• W202947524 cites W2016630957 @default.
• W202947524 cites W2019877982 @default.
• W202947524 cites W2023263545 @default.
• W202947524 cites W2025354784 @default.
• W202947524 cites W2044832082 @default.
• W202947524 cites W2045287165 @default.
• W202947524 cites W2049059366 @default.
• W202947524 cites W2058474512 @default.
• W202947524 cites W2062694318 @default.
• W202947524 cites W206500672 @default.
• W202947524 cites W2071350161 @default.
• W202947524 cites W2081935437 @default.
• W202947524 cites W2089813543 @default.
• W202947524 cites W2092092717 @default.
• W202947524 cites W2106053019 @default.
• W202947524 cites W2120787036 @default.
• W202947524 cites W2138486032 @default.
• W202947524 cites W2151634273 @default.
• W202947524 cites W2182154297 @default.
• W202947524 cites W2182578622 @default.
• W202947524 cites W2262241006 @default.
• W202947524 cites W2315224527 @default.
• W202947524 cites W2328047889 @default.
• W202947524 cites W2338969114 @default.
• W202947524 cites W2407663030 @default.
• W202947524 cites W2414074028 @default.
• W202947524 cites W2415980691 @default.
• W202947524 cites W2416381199 @default.
• W202947524 cites W2418953808 @default.
• W202947524 cites W2894728117 @default.
• W202947524 cites W2898057367 @default.
• W202947524 cites W88659288 @default.
• W202947524 doi "https://doi.org/10.1182/blood.v55.2.338.338" @default.
• W202947524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7353076" @default.
• W202947524 hasPublicationYear "1980" @default.
• W202947524 type Work @default.
• W202947524 sameAs 202947524 @default.
• W202947524 citedByCount "56" @default.
• W202947524 countsByYear W2029475242012 @default.
• W202947524 countsByYear W2029475242019 @default.
• W202947524 crossrefType "journal-article" @default.
• W202947524 hasAuthorship W202947524A5008970027 @default.
• W202947524 hasAuthorship W202947524A5024968001 @default.
• W202947524 hasAuthorship W202947524A5088809773 @default.
• W202947524 hasBestOaLocation W2029475241 @default.
• W202947524 hasConcept C160448771 @default.
• W202947524 hasConcept C171779818 @default.
• W202947524 hasConcept C185592680 @default.
• W202947524 hasConcept C198677920 @default.
• W202947524 hasConcept C202751555 @default.
• W202947524 hasConcept C203014093 @default.
• W202947524 hasConcept C2776342803 @default.
• W202947524 hasConcept C2776914184 @default.
• W202947524 hasConcept C2777700362 @default.
• W202947524 hasConcept C2777983669 @default.
• W202947524 hasConcept C3019673159 @default.
• W202947524 hasConcept C53122370 @default.
• W202947524 hasConcept C55493867 @default.
• W202947524 hasConcept C57600042 @default.
• W202947524 hasConcept C71924100 @default.
• W202947524 hasConcept C86803240 @default.
• W202947524 hasConcept C8891405 @default.
• W202947524 hasConceptScore W202947524C160448771 @default.
• W202947524 hasConceptScore W202947524C171779818 @default.
• W202947524 hasConceptScore W202947524C185592680 @default.
• W202947524 hasConceptScore W202947524C198677920 @default.
• W202947524 hasConceptScore W202947524C202751555 @default.
• W202947524 hasConceptScore W202947524C203014093 @default.
• W202947524 hasConceptScore W202947524C2776342803 @default.
• W202947524 hasConceptScore W202947524C2776914184 @default.
• W202947524 hasConceptScore W202947524C2777700362 @default.
• W202947524 hasConceptScore W202947524C2777983669 @default.
• W202947524 hasConceptScore W202947524C3019673159 @default.
• W202947524 hasConceptScore W202947524C53122370 @default.
• W202947524 hasConceptScore W202947524C55493867 @default.
• W202947524 hasConceptScore W202947524C57600042 @default.
• W202947524 hasConceptScore W202947524C71924100 @default.
• W202947524 hasConceptScore W202947524C86803240 @default.
• W202947524 hasConceptScore W202947524C8891405 @default.
• W202947524 hasIssue "2" @default.
• W202947524 hasLocation W2029475241 @default.
• W202947524 hasOpenAccess W202947524 @default.
• W202947524 hasPrimaryLocation W2029475241 @default.

• next