FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029477181> ?p ?o ?g. }

• W2029477181 endingPage "76" @default.
• W2029477181 startingPage "67" @default.
• W2029477181 abstract "During the luteal phase of the menstrual cycle, plasma progesterone (P) and estradiol (E2) concentrations are elevated, and LH (and by inference GnRH) pulse frequency is slow. In contrast, LH pulse frequency increases during the early follicular phase when plasma E2 and P are lower. To examine the mechanism(s) responsible for the slower GnRH pulse frequency in the luteal phase, we maintained plasma P, E2, or both at midluteal concentrations from the midluteal phase to the time of the next early follicular phase and measured the effects on LH secretion. Thirteen normal women with regular menstrual cycles were studied during two or three cycles. Blood was obtained every 10 min during 10-h studies. Control cycle luteal and early follicular studies were followed by a second control study in the luteal phase of the treatment cycle. P (six women), E2 (seven women), or both (five women) then were given twice daily by im injection for 6-12 days until the day corresponding to the early follicular study of the control cycle (EF + P, EF + E2, or EF + E2 + P). A final study was performed 1 week after the injections were discontinued (F). LH pulse frequency was low in the midluteal phase [3.2 +/- 0.2 (+/- SE) pulses/10 h] and increased by the early follicular phase (8.0 +/- 0.8 pulses/10 h) in the control cycles. The increase in LH pulse frequency was not significantly inhibited by administration of P (6.7 +/- 0.7 pulses/10 h; EF + P). However, during both E2 alone and E2 + P, LH pulse frequency remained low (EF + E2, 3.6 +/- 0.8; EF + E2 + P, 2.0 +/- 0.7 pulses/10 h). The mean plasma FSH concentrations paralleled changes in LH pulse frequency, increasing from the luteal to the early follicular phase in the control cycles and during P injections and remaining low during E2 and E2 + P injections. We conclude that continued exposure to P alone does not maintain GnRH pulse frequency at midluteal phase values and that any effect of P requires the presence of E2. As E2 alone maintained lower LH pulse frequency, E2 may act directly to decrease the pulsatile GnRH secretion or it may potentiate the effects of low (less than 3.2 nmol/L) P concentrations." @default.
• W2029477181 created "2016-06-24" @default.
• W2029477181 creator A5020447150 @default.
• W2029477181 creator A5042782521 @default.
• W2029477181 creator A5070604004 @default.
• W2029477181 creator A5076245764 @default.
• W2029477181 date "1989-07-01" @default.
• W2029477181 modified "2023-10-15" @default.
• W2029477181 title "The Roles of Estradiol and Progesterone in Decreasing Luteinizing Hormone Pulse Frequency in the Luteal Phase of the Menstrual Cycle*" @default.
• W2029477181 cites W1964179717 @default.
• W2029477181 cites W1964296327 @default.
• W2029477181 cites W1967685136 @default.
• W2029477181 cites W1968346194 @default.
• W2029477181 cites W1972181075 @default.
• W2029477181 cites W1974171474 @default.
• W2029477181 cites W1978086274 @default.
• W2029477181 cites W1986228655 @default.
• W2029477181 cites W1990158407 @default.
• W2029477181 cites W1991000644 @default.
• W2029477181 cites W1992462878 @default.
• W2029477181 cites W1992779076 @default.
• W2029477181 cites W1996671215 @default.
• W2029477181 cites W2008733524 @default.
• W2029477181 cites W2009553345 @default.
• W2029477181 cites W2013505911 @default.
• W2029477181 cites W2023097658 @default.
• W2029477181 cites W2024100619 @default.
• W2029477181 cites W2041122938 @default.
• W2029477181 cites W2041132592 @default.
• W2029477181 cites W2043060055 @default.
• W2029477181 cites W2059011677 @default.
• W2029477181 cites W2059596300 @default.
• W2029477181 cites W2063774585 @default.
• W2029477181 cites W2065295152 @default.
• W2029477181 cites W2065369379 @default.
• W2029477181 cites W2065442262 @default.
• W2029477181 cites W2068905948 @default.
• W2029477181 cites W2070745891 @default.
• W2029477181 cites W2071599591 @default.
• W2029477181 cites W2074607818 @default.
• W2029477181 cites W2081626609 @default.
• W2029477181 cites W2100100394 @default.
• W2029477181 cites W2105624384 @default.
• W2029477181 cites W2107040028 @default.
• W2029477181 cites W2119850496 @default.
• W2029477181 cites W2127309304 @default.
• W2029477181 cites W2135348351 @default.
• W2029477181 cites W2158892504 @default.
• W2029477181 cites W2441515707 @default.
• W2029477181 cites W8031503 @default.
• W2029477181 doi "https://doi.org/10.1210/jcem-69-1-67" @default.
• W2029477181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2499593" @default.
• W2029477181 hasPublicationYear "1989" @default.
• W2029477181 type Work @default.
• W2029477181 sameAs 2029477181 @default.
• W2029477181 citedByCount "107" @default.
• W2029477181 countsByYear W20294771812012 @default.
• W2029477181 countsByYear W20294771812013 @default.
• W2029477181 countsByYear W20294771812014 @default.
• W2029477181 countsByYear W20294771812015 @default.
• W2029477181 countsByYear W20294771812016 @default.
• W2029477181 countsByYear W20294771812017 @default.
• W2029477181 countsByYear W20294771812018 @default.
• W2029477181 countsByYear W20294771812019 @default.
• W2029477181 countsByYear W20294771812020 @default.
• W2029477181 countsByYear W20294771812021 @default.
• W2029477181 countsByYear W20294771812022 @default.
• W2029477181 crossrefType "journal-article" @default.
• W2029477181 hasAuthorship W2029477181A5020447150 @default.
• W2029477181 hasAuthorship W2029477181A5042782521 @default.
• W2029477181 hasAuthorship W2029477181A5070604004 @default.
• W2029477181 hasAuthorship W2029477181A5076245764 @default.
• W2029477181 hasConcept C126322002 @default.
• W2029477181 hasConcept C134018914 @default.
• W2029477181 hasConcept C143228043 @default.
• W2029477181 hasConcept C185592680 @default.
• W2029477181 hasConcept C187785154 @default.
• W2029477181 hasConcept C2777164284 @default.
• W2029477181 hasConcept C2778575703 @default.
• W2029477181 hasConcept C2778782382 @default.
• W2029477181 hasConcept C2779058012 @default.
• W2029477181 hasConcept C71315377 @default.
• W2029477181 hasConcept C71924100 @default.
• W2029477181 hasConcept C86803240 @default.
• W2029477181 hasConceptScore W2029477181C126322002 @default.
• W2029477181 hasConceptScore W2029477181C134018914 @default.
• W2029477181 hasConceptScore W2029477181C143228043 @default.
• W2029477181 hasConceptScore W2029477181C185592680 @default.
• W2029477181 hasConceptScore W2029477181C187785154 @default.
• W2029477181 hasConceptScore W2029477181C2777164284 @default.
• W2029477181 hasConceptScore W2029477181C2778575703 @default.
• W2029477181 hasConceptScore W2029477181C2778782382 @default.
• W2029477181 hasConceptScore W2029477181C2779058012 @default.
• W2029477181 hasConceptScore W2029477181C71315377 @default.
• W2029477181 hasConceptScore W2029477181C71924100 @default.
• W2029477181 hasConceptScore W2029477181C86803240 @default.
• W2029477181 hasIssue "1" @default.
• W2029477181 hasLocation W20294771811 @default.

• next