Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029486073> ?p ?o ?g. }
- W2029486073 endingPage "169" @default.
- W2029486073 startingPage "165" @default.
- W2029486073 abstract "Objective: Antiendomysial antibody (EMA) production has been induced in vitro by the small bowel mucosa of celiac disease (CD) patients in clinical remission cultured in the presence of gliadin peptides. The aim of the present study was to use this in vitro system to determine whether it could be used to predict the clinical or histologic relapse to gluten challenge in CD children on a gluten-free diet (GFD). Methods: Enrolled were 32 CD children and adolescents on GFD (group 1), and 80 controls (group 2) who underwent in vitro gliadin challenge. Subsequently, 24 group 1 CD children underwent in vivo gluten challenge to confirm the diagnosis. Biopsy cultures, with and without gliadin, morphometric analysis, immunoglobulin (Ig)A and IgG1 EMA detection, both in sera and culture supernatants, were performed. Results: Of the 32 group 1 CD patients, 23 were IgA EMA positive in culture supernatants. The other nine were IgG1 EMA positive. All 24 children who had in vivo gluten challenge showed clinical or histologic relapse. All culture supernatants from disease controls belonging to group 2 were both IgA and IgG1 EMA negative, irrespective of gliadin challenge. Conclusions: Organ culture with in vitro gliadin challenge is able to reproduce the results of in vivo challenge. This system could reduce the need for gluten challenge in celiac children." @default.
- W2029486073 created "2016-06-24" @default.
- W2029486073 creator A5000100520 @default.
- W2029486073 creator A5021553335 @default.
- W2029486073 creator A5031326868 @default.
- W2029486073 creator A5046977360 @default.
- W2029486073 creator A5061464801 @default.
- W2029486073 creator A5063540783 @default.
- W2029486073 creator A5066814471 @default.
- W2029486073 creator A5070257447 @default.
- W2029486073 date "2005-02-01" @default.
- W2029486073 modified "2023-09-26" @default.
- W2029486073 title "Antiendomysial Antibody Detection in Biopsy Culture Allows Avoidance of Gluten Challenge in Celiac Children" @default.
- W2029486073 cites W1938846626 @default.
- W2029486073 cites W1970768730 @default.
- W2029486073 cites W1981788459 @default.
- W2029486073 cites W1987433373 @default.
- W2029486073 cites W2001860298 @default.
- W2029486073 cites W2006713555 @default.
- W2029486073 cites W2025972539 @default.
- W2029486073 cites W2036798664 @default.
- W2029486073 cites W2041280764 @default.
- W2029486073 cites W2041532720 @default.
- W2029486073 cites W2048716205 @default.
- W2029486073 cites W2053071066 @default.
- W2029486073 cites W2055104936 @default.
- W2029486073 cites W2061361616 @default.
- W2029486073 cites W2066932270 @default.
- W2029486073 cites W2088417074 @default.
- W2029486073 cites W2106951285 @default.
- W2029486073 cites W2111948337 @default.
- W2029486073 cites W2124295431 @default.
- W2029486073 cites W2144071099 @default.
- W2029486073 cites W2162196677 @default.
- W2029486073 cites W2315194442 @default.
- W2029486073 cites W2317664719 @default.
- W2029486073 cites W2327043902 @default.
- W2029486073 cites W2328588151 @default.
- W2029486073 cites W4240843945 @default.
- W2029486073 doi "https://doi.org/10.1097/00005176-200502000-00015" @default.
- W2029486073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15699690" @default.
- W2029486073 hasPublicationYear "2005" @default.
- W2029486073 type Work @default.
- W2029486073 sameAs 2029486073 @default.
- W2029486073 citedByCount "11" @default.
- W2029486073 countsByYear W20294860732012 @default.
- W2029486073 countsByYear W20294860732013 @default.
- W2029486073 countsByYear W20294860732016 @default.
- W2029486073 crossrefType "journal-article" @default.
- W2029486073 hasAuthorship W2029486073A5000100520 @default.
- W2029486073 hasAuthorship W2029486073A5021553335 @default.
- W2029486073 hasAuthorship W2029486073A5031326868 @default.
- W2029486073 hasAuthorship W2029486073A5046977360 @default.
- W2029486073 hasAuthorship W2029486073A5061464801 @default.
- W2029486073 hasAuthorship W2029486073A5063540783 @default.
- W2029486073 hasAuthorship W2029486073A5066814471 @default.
- W2029486073 hasAuthorship W2029486073A5070257447 @default.
- W2029486073 hasBestOaLocation W20294860731 @default.
- W2029486073 hasConcept C126322002 @default.
- W2029486073 hasConcept C142724271 @default.
- W2029486073 hasConcept C150903083 @default.
- W2029486073 hasConcept C159654299 @default.
- W2029486073 hasConcept C202751555 @default.
- W2029486073 hasConcept C203014093 @default.
- W2029486073 hasConcept C207001950 @default.
- W2029486073 hasConcept C2775934546 @default.
- W2029486073 hasConcept C2776336767 @default.
- W2029486073 hasConcept C2779134260 @default.
- W2029486073 hasConcept C2780092158 @default.
- W2029486073 hasConcept C2780349322 @default.
- W2029486073 hasConcept C2780648854 @default.
- W2029486073 hasConcept C3019118998 @default.
- W2029486073 hasConcept C55493867 @default.
- W2029486073 hasConcept C71924100 @default.
- W2029486073 hasConcept C86803240 @default.
- W2029486073 hasConcept C90924648 @default.
- W2029486073 hasConceptScore W2029486073C126322002 @default.
- W2029486073 hasConceptScore W2029486073C142724271 @default.
- W2029486073 hasConceptScore W2029486073C150903083 @default.
- W2029486073 hasConceptScore W2029486073C159654299 @default.
- W2029486073 hasConceptScore W2029486073C202751555 @default.
- W2029486073 hasConceptScore W2029486073C203014093 @default.
- W2029486073 hasConceptScore W2029486073C207001950 @default.
- W2029486073 hasConceptScore W2029486073C2775934546 @default.
- W2029486073 hasConceptScore W2029486073C2776336767 @default.
- W2029486073 hasConceptScore W2029486073C2779134260 @default.
- W2029486073 hasConceptScore W2029486073C2780092158 @default.
- W2029486073 hasConceptScore W2029486073C2780349322 @default.
- W2029486073 hasConceptScore W2029486073C2780648854 @default.
- W2029486073 hasConceptScore W2029486073C3019118998 @default.
- W2029486073 hasConceptScore W2029486073C55493867 @default.
- W2029486073 hasConceptScore W2029486073C71924100 @default.
- W2029486073 hasConceptScore W2029486073C86803240 @default.
- W2029486073 hasConceptScore W2029486073C90924648 @default.
- W2029486073 hasIssue "2" @default.
- W2029486073 hasLocation W20294860731 @default.
- W2029486073 hasLocation W20294860732 @default.
- W2029486073 hasOpenAccess W2029486073 @default.