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- W2029492830 abstract "Natural killer (NK) cells are critical for the first-line defense in infection. Treated viremic HIV-1 infection is associated with the expansion of an anergic subset of CD3−CD56−CD16+ NK cells unable to respond to stimulation with MHC-devoid target cells or with mitogens. These CD3−CD56−CD16+ NK cells expressed SHIP-1 and had significantly reduced perforin levels. This observation suggests a mechanism for the reduced functional activity of CD3−CD56−CD16+ NK cells in chronic HIV-1 infection." @default.
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- W2029492830 date "2006-07-13" @default.
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- W2029492830 title "Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection" @default.
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- W2029492830 doi "https://doi.org/10.1097/01.aids.0000237371.31315.48" @default.
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