FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029494385> ?p ?o ?g. }

• W2029494385 endingPage "40" @default.
• W2029494385 startingPage "37" @default.
• W2029494385 abstract "Reactive oxygen species have been implicated in the pathogenesis of hypoxia-reoxygenation injury. Previously, we demonstrated that 2:1 catecholic iron complexes were more effective than uncomplexed catechols at (a) scavenging superoxide radicals generated enzymatically, and (b) protecting hepatocytes against hypoxia-reoxygenation injury [25]. Based on these findings, we sought to demonstrate similar effects using catecholamine neurotransmitters. Various catecholamine-iron complexes were shown to be more effective than uncomplexed catecholamines at scavenging superoxide radicals and could be used to protect cells from hypoxia-reoxygenation injury. α-Methyl-3,4-dihydroxyphenylalanine (α-methylDOPA) complexed with ferric ion (2:1) showed the greatest superoxide scavenging potency amongst the catecholamine-iron complexes. The uncomplexed catecholamines were much less effective at scavenging superoxide radicals than the iron-catecholamine complexes. Dopamine was the most effective superoxide scavenger among the uncomplexed catecholamines. The superoxide scavenging effectiveness of the latter seemed to correlate with their reduction potentials, but not directly to their pKa values. Furthermore, dopamine:iron(III) complex protected isolated hepatocytes against hypoxia-reoxygenation injury at concentrations four-fold lower than that required for protection by dopamine alone." @default.
• W2029494385 created "2016-06-24" @default.
• W2029494385 creator A5058904298 @default.
• W2029494385 creator A5063396591 @default.
• W2029494385 creator A5077618957 @default.
• W2029494385 date "2000-12-01" @default.
• W2029494385 modified "2023-10-12" @default.
• W2029494385 title "Superoxide radical scavenging and attenuation of hypoxia-reoxygenation injury by neurotransmitter ferric complexes in isolated rat hepatocytes" @default.
• W2029494385 cites W1975672376 @default.
• W2029494385 cites W1977084589 @default.
• W2029494385 cites W1979424160 @default.
• W2029494385 cites W1981399112 @default.
• W2029494385 cites W1988951836 @default.
• W2029494385 cites W1999323692 @default.
• W2029494385 cites W2007663048 @default.
• W2029494385 cites W2019429562 @default.
• W2029494385 cites W2024761184 @default.
• W2029494385 cites W2029649014 @default.
• W2029494385 cites W2053733534 @default.
• W2029494385 cites W2055357235 @default.
• W2029494385 cites W2063014167 @default.
• W2029494385 cites W2063746042 @default.
• W2029494385 cites W2069216456 @default.
• W2029494385 cites W2078700124 @default.
• W2029494385 cites W2085304244 @default.
• W2029494385 cites W2090967079 @default.
• W2029494385 cites W2115231900 @default.
• W2029494385 cites W3139092472 @default.
• W2029494385 doi "https://doi.org/10.1016/s0304-3940(00)01618-9" @default.
• W2029494385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11099828" @default.
• W2029494385 hasPublicationYear "2000" @default.
• W2029494385 type Work @default.
• W2029494385 sameAs 2029494385 @default.
• W2029494385 citedByCount "24" @default.
• W2029494385 countsByYear W20294943852012 @default.
• W2029494385 countsByYear W20294943852013 @default.
• W2029494385 countsByYear W20294943852014 @default.
• W2029494385 countsByYear W20294943852015 @default.
• W2029494385 countsByYear W20294943852016 @default.
• W2029494385 countsByYear W20294943852017 @default.
• W2029494385 countsByYear W20294943852021 @default.
• W2029494385 crossrefType "journal-article" @default.
• W2029494385 hasAuthorship W2029494385A5058904298 @default.
• W2029494385 hasAuthorship W2029494385A5063396591 @default.
• W2029494385 hasAuthorship W2029494385A5077618957 @default.
• W2029494385 hasConcept C134018914 @default.
• W2029494385 hasConcept C139066938 @default.
• W2029494385 hasConcept C170493617 @default.
• W2029494385 hasConcept C178790620 @default.
• W2029494385 hasConcept C181199279 @default.
• W2029494385 hasConcept C185592680 @default.
• W2029494385 hasConcept C2775894120 @default.
• W2029494385 hasConcept C2776219046 @default.
• W2029494385 hasConcept C2780534640 @default.
• W2029494385 hasConcept C2780795997 @default.
• W2029494385 hasConcept C48349386 @default.
• W2029494385 hasConcept C513476851 @default.
• W2029494385 hasConcept C540031477 @default.
• W2029494385 hasConcept C55493867 @default.
• W2029494385 hasConcept C7836513 @default.
• W2029494385 hasConcept C86803240 @default.
• W2029494385 hasConcept C98274493 @default.
• W2029494385 hasConceptScore W2029494385C134018914 @default.
• W2029494385 hasConceptScore W2029494385C139066938 @default.
• W2029494385 hasConceptScore W2029494385C170493617 @default.
• W2029494385 hasConceptScore W2029494385C178790620 @default.
• W2029494385 hasConceptScore W2029494385C181199279 @default.
• W2029494385 hasConceptScore W2029494385C185592680 @default.
• W2029494385 hasConceptScore W2029494385C2775894120 @default.
• W2029494385 hasConceptScore W2029494385C2776219046 @default.
• W2029494385 hasConceptScore W2029494385C2780534640 @default.
• W2029494385 hasConceptScore W2029494385C2780795997 @default.
• W2029494385 hasConceptScore W2029494385C48349386 @default.
• W2029494385 hasConceptScore W2029494385C513476851 @default.
• W2029494385 hasConceptScore W2029494385C540031477 @default.
• W2029494385 hasConceptScore W2029494385C55493867 @default.
• W2029494385 hasConceptScore W2029494385C7836513 @default.
• W2029494385 hasConceptScore W2029494385C86803240 @default.
• W2029494385 hasConceptScore W2029494385C98274493 @default.
• W2029494385 hasIssue "1" @default.
• W2029494385 hasLocation W20294943851 @default.
• W2029494385 hasLocation W20294943852 @default.
• W2029494385 hasOpenAccess W2029494385 @default.
• W2029494385 hasPrimaryLocation W20294943851 @default.
• W2029494385 hasRelatedWork W2007070932 @default.
• W2029494385 hasRelatedWork W2025098696 @default.
• W2029494385 hasRelatedWork W2037157726 @default.
• W2029494385 hasRelatedWork W2051208451 @default.
• W2029494385 hasRelatedWork W2059890146 @default.
• W2029494385 hasRelatedWork W2062709989 @default.
• W2029494385 hasRelatedWork W2147934559 @default.
• W2029494385 hasRelatedWork W2355569103 @default.
• W2029494385 hasRelatedWork W2359308559 @default.
• W2029494385 hasRelatedWork W2403625851 @default.
• W2029494385 hasVolume "296" @default.
• W2029494385 isParatext "false" @default.
• W2029494385 isRetracted "false" @default.
• W2029494385 magId "2029494385" @default.

• next