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- W2029553886 abstract "SummaryThe authors carried out experiments on 82 guinea-pigs for the purpose of eliciting hydralazine erythematodes. Apresolin was administered per os in large doses, and injected together with incomplete Freund's adjuvant in smaller doses. The experiment lasted from 7 to 16 months. The authors succeeded in bringing about SLE-like disease in 17—23 % of the animals. In addition to the serologic and clinical positivity, non-specific tissue changes of polyvisceral character were also observed. As regards eliciting the clinical picture the authors stress the significance of the immune-pathomechanism rather than the role of the toxic factor." @default.
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- W2029553886 date "1967-12-01" @default.
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- W2029553886 title "Experimental “Hydralazine Erythematodes” of the Guinea-Pig" @default.
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- W2029553886 doi "https://doi.org/10.3109/rhe1.1967.13.issue-1-4.12" @default.
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