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- W2029555783 abstract "Objective: To prospectively evaluate the biochemical status of vitamins A, D, and E in children with cystic fibrosis (CF). Subjects: A total of 127 infants identified by the Colorado CF newborn screening program. Design: Vitamin status (serum ret-inol, 25-hydroxy vitamin D, ratio of alpha-tocopherol/total lipids) and serum albumin were assessed at diagnosis (4 to 8 weeks), ages 6 months, 12 months, and yearly thereafter, to age 10 years. Results: Deficiency of 1 or more vitamins was present in 44 (45.8%) of 96 patients at age 4 to 8 weeks as follows: vitamin A 29.07c, vitamin D 22.5%, and vitamin E 22.8%. Of these patients with initial deficiency, the percent that was deficient at 1 or more subsequent time points, despite supplementation, was vitamin A 11.1%, vitamin D 12.5%, and vitamin E 57.1%. Of the initial patients with vitamin sufficiency, the percent who became deficient at any time during the 10-year period was as follows: vitamin A 4.5%, vitamin D 14.4%, and vitamin E 11.8%. The percent of patients deficient for 1 or more vitamins ranged from" @default.
- W2029555783 created "2016-06-24" @default.
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- W2029555783 date "2000-08-01" @default.
- W2029555783 modified "2023-09-26" @default.
- W2029555783 title "Prospective, Long-Term Study of Fat-soluble Vitamin Status in Children with Cystic Fibrosis Identified by Newborn Screen" @default.
- W2029555783 doi "https://doi.org/10.1177/088453360001500413" @default.
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