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- W2029557523 abstract "Recent studies have proposed an interrelation between the brain-derived neurotrophic factor (BDNF) val66met polymorphism and the serotonin system. In this study, we investigated whether the BDNF val66met polymorphism or blood BDNF levels are associated with cerebral 5-hydroxytryptamine 2A (5-HT 2A ) receptor or serotonin transporter (SERT) binding in healthy subjects. No statistically significant differences in 5-HT 2A receptor or SERT binding were found between the val/val and met carriers, nor were blood BDNF values associated with SERT binding or 5-HT 2A receptor binding. In conclusion, val66met BDNF polymorphism status is not associated with changes in the serotonergic system. Moreover, BDNF levels in blood do not correlate with either 5-HT 2A or SERT binding." @default.
- W2029557523 created "2016-06-24" @default.
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- W2029557523 date "2010-08-25" @default.
- W2029557523 modified "2023-10-18" @default.
- W2029557523 title "Cerebral 5-HT<sub>2A</sub> Receptor and Serotonin Transporter Binding in Humans Are Not Affected by the val66met BDNF Polymorphism Status or Blood BDNF Levels" @default.
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- W2029557523 doi "https://doi.org/10.1038/jcbfm.2010.114" @default.
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