FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029557687> ?p ?o ?g. }

• W2029557687 endingPage "194" @default.
• W2029557687 startingPage "188" @default.
• W2029557687 abstract "Phosphine (PH3) fumigation is the primary method worldwide for controlling insect pests of stored commodities. Over-reliance on phosphine, however, has led to the emergence of strong resistance. Detailed genetic studies previously identified two loci, rph1 and rph2, that interact synergistically to create a strong resistance phenotype. We compared the genetics of phosphine resistance in strains of Rhyzopertha dominica and Tribolium castaneum from India and Australia, countries having similar pest species but widely differing in pest management practices. Sequencing analysis of the rph2 locus, dihydrolipoamide dehydrogenase (dld), identified two structurally equivalent variants, Proline49>Serine (P49S) in one R. dominica strain and P45S in three strains of T. castaneum from India. These variants of the DLD protein likely affect FAD cofactor interaction with the enzyme. A survey of insects from storage facilities across southern India revealed that the P45/49S variant is distributed throughout the region at very high frequencies, in up to 94% of R. dominica and 97% of T. castaneum in the state of Tamil Nadu. The abundance of the P45/49S variant in insect populations contrasted sharply with the evolutionary record in which the variant was absent from eukaryotic DLD sequences. This suggests that the variant is unlikely to provide a strong selective advantage in the absence of phosphine fumigation." @default.
• W2029557687 created "2016-06-24" @default.
• W2029557687 creator A5025199106 @default.
• W2029557687 creator A5028573492 @default.
• W2029557687 creator A5033374633 @default.
• W2029557687 creator A5036226265 @default.
• W2029557687 creator A5058409916 @default.
• W2029557687 creator A5069079031 @default.
• W2029557687 creator A5073704107 @default.
• W2029557687 creator A5074629680 @default.
• W2029557687 creator A5090714022 @default.
• W2029557687 creator A5091427225 @default.
• W2029557687 date "2015-04-08" @default.
• W2029557687 modified "2023-10-10" @default.
• W2029557687 title "Phosphine resistance in India is characterised by a dihydrolipoamide dehydrogenase variant that is otherwise unobserved in eukaryotes" @default.
• W2029557687 cites W1517812011 @default.
• W2029557687 cites W1534555090 @default.
• W2029557687 cites W1751735648 @default.
• W2029557687 cites W1986033742 @default.
• W2029557687 cites W2008294932 @default.
• W2029557687 cites W2024385313 @default.
• W2029557687 cites W2036168763 @default.
• W2029557687 cites W2040750333 @default.
• W2029557687 cites W2042832069 @default.
• W2029557687 cites W2049175620 @default.
• W2029557687 cites W2051111844 @default.
• W2029557687 cites W2088919353 @default.
• W2029557687 cites W2108294918 @default.
• W2029557687 cites W2117297710 @default.
• W2029557687 cites W2123036062 @default.
• W2029557687 cites W2128813668 @default.
• W2029557687 cites W2136583728 @default.
• W2029557687 cites W2144622999 @default.
• W2029557687 cites W2148934230 @default.
• W2029557687 cites W2155322411 @default.
• W2029557687 cites W2161806181 @default.
• W2029557687 doi "https://doi.org/10.1038/hdy.2015.24" @default.
• W2029557687 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4814238" @default.
• W2029557687 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25853517" @default.
• W2029557687 hasPublicationYear "2015" @default.
• W2029557687 type Work @default.
• W2029557687 sameAs 2029557687 @default.
• W2029557687 citedByCount "61" @default.
• W2029557687 countsByYear W20295576872016 @default.
• W2029557687 countsByYear W20295576872017 @default.
• W2029557687 countsByYear W20295576872018 @default.
• W2029557687 countsByYear W20295576872019 @default.
• W2029557687 countsByYear W20295576872020 @default.
• W2029557687 countsByYear W20295576872021 @default.
• W2029557687 countsByYear W20295576872022 @default.
• W2029557687 countsByYear W20295576872023 @default.
• W2029557687 crossrefType "journal-article" @default.
• W2029557687 hasAuthorship W2029557687A5025199106 @default.
• W2029557687 hasAuthorship W2029557687A5028573492 @default.
• W2029557687 hasAuthorship W2029557687A5033374633 @default.
• W2029557687 hasAuthorship W2029557687A5036226265 @default.
• W2029557687 hasAuthorship W2029557687A5058409916 @default.
• W2029557687 hasAuthorship W2029557687A5069079031 @default.
• W2029557687 hasAuthorship W2029557687A5073704107 @default.
• W2029557687 hasAuthorship W2029557687A5074629680 @default.
• W2029557687 hasAuthorship W2029557687A5090714022 @default.
• W2029557687 hasAuthorship W2029557687A5091427225 @default.
• W2029557687 hasBestOaLocation W20295576871 @default.
• W2029557687 hasConcept C104317684 @default.
• W2029557687 hasConcept C150903083 @default.
• W2029557687 hasConcept C161790260 @default.
• W2029557687 hasConcept C18903297 @default.
• W2029557687 hasConcept C22508944 @default.
• W2029557687 hasConcept C2777716191 @default.
• W2029557687 hasConcept C2780897802 @default.
• W2029557687 hasConcept C54355233 @default.
• W2029557687 hasConcept C55493867 @default.
• W2029557687 hasConcept C59822182 @default.
• W2029557687 hasConcept C84597430 @default.
• W2029557687 hasConcept C86803240 @default.
• W2029557687 hasConceptScore W2029557687C104317684 @default.
• W2029557687 hasConceptScore W2029557687C150903083 @default.
• W2029557687 hasConceptScore W2029557687C161790260 @default.
• W2029557687 hasConceptScore W2029557687C18903297 @default.
• W2029557687 hasConceptScore W2029557687C22508944 @default.
• W2029557687 hasConceptScore W2029557687C2777716191 @default.
• W2029557687 hasConceptScore W2029557687C2780897802 @default.
• W2029557687 hasConceptScore W2029557687C54355233 @default.
• W2029557687 hasConceptScore W2029557687C55493867 @default.
• W2029557687 hasConceptScore W2029557687C59822182 @default.
• W2029557687 hasConceptScore W2029557687C84597430 @default.
• W2029557687 hasConceptScore W2029557687C86803240 @default.
• W2029557687 hasIssue "3" @default.
• W2029557687 hasLocation W20295576871 @default.
• W2029557687 hasLocation W20295576872 @default.
• W2029557687 hasLocation W20295576873 @default.
• W2029557687 hasLocation W20295576874 @default.
• W2029557687 hasOpenAccess W2029557687 @default.
• W2029557687 hasPrimaryLocation W20295576871 @default.
• W2029557687 hasRelatedWork W1553684855 @default.
• W2029557687 hasRelatedWork W1828691184 @default.
• W2029557687 hasRelatedWork W2029138456 @default.
• W2029557687 hasRelatedWork W2055870918 @default.

• next