Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029566067> ?p ?o ?g. }
- W2029566067 endingPage "50" @default.
- W2029566067 startingPage "45" @default.
- W2029566067 abstract "The aim of this study was to investigate the cytotoxic and genotoxic effect of copper extracts obtained from metallic copper in Chinese hamster ovary (CHO-K1) cell line using neutral red (NR), sister chromatid exchange (SCE), chromosomal aberrations (CA) and cell-cycle kinetics tests. Cells were cultured in Ham-F10 with different copper-containing extracts obtained after the immersion of copper disks for 1, 2, 3, 9, 12, 24, 48 and 72 h in culture medium. Results from cytotoxicity assay showed an inverted U-shape response evidenced in changes in lysosomal activity and mitotic index. The analysis of CA revealed an increase of abnormal metaphases for copper concentration (cCu) in the 5.67–7.42 mg/L dose-range (p < 0.001). In addition, SCE frequencies were higher for treated cells when compared with controls in the 1.56–7.42 mg/L concentration range (p < 0.001). The absence of metaphases indicated cytotoxicity for cCu ≥ 10.85 mg/L. Results show that cells close to copper-containing materials releasing copper ions are susceptible to cytotoxic and genotoxic effects." @default.
- W2029566067 created "2016-06-24" @default.
- W2029566067 creator A5008756451 @default.
- W2029566067 creator A5031962646 @default.
- W2029566067 creator A5087086934 @default.
- W2029566067 date "2009-01-01" @default.
- W2029566067 modified "2023-10-06" @default.
- W2029566067 title "Effects of copper ions released from metallic copper on CHO-K1 cells" @default.
- W2029566067 cites W1906847803 @default.
- W2029566067 cites W1964466197 @default.
- W2029566067 cites W1966882563 @default.
- W2029566067 cites W1969280450 @default.
- W2029566067 cites W1984793006 @default.
- W2029566067 cites W1989225220 @default.
- W2029566067 cites W1990275971 @default.
- W2029566067 cites W1993864942 @default.
- W2029566067 cites W1995277333 @default.
- W2029566067 cites W1997129200 @default.
- W2029566067 cites W2002628729 @default.
- W2029566067 cites W2004597396 @default.
- W2029566067 cites W2004898039 @default.
- W2029566067 cites W2006715206 @default.
- W2029566067 cites W2010818369 @default.
- W2029566067 cites W2013518860 @default.
- W2029566067 cites W2015476056 @default.
- W2029566067 cites W2018439122 @default.
- W2029566067 cites W2025900004 @default.
- W2029566067 cites W2028045940 @default.
- W2029566067 cites W2031978635 @default.
- W2029566067 cites W2033994951 @default.
- W2029566067 cites W2036141401 @default.
- W2029566067 cites W2037905608 @default.
- W2029566067 cites W2040471655 @default.
- W2029566067 cites W2040713211 @default.
- W2029566067 cites W2042675162 @default.
- W2029566067 cites W2047475165 @default.
- W2029566067 cites W2047558574 @default.
- W2029566067 cites W2048608979 @default.
- W2029566067 cites W2053331671 @default.
- W2029566067 cites W2055376998 @default.
- W2029566067 cites W2059073584 @default.
- W2029566067 cites W2064578882 @default.
- W2029566067 cites W2067140634 @default.
- W2029566067 cites W2070744125 @default.
- W2029566067 cites W2072755009 @default.
- W2029566067 cites W2081376165 @default.
- W2029566067 cites W2086854084 @default.
- W2029566067 cites W2090963715 @default.
- W2029566067 cites W2094825909 @default.
- W2029566067 cites W2113522288 @default.
- W2029566067 cites W2123046528 @default.
- W2029566067 cites W2136210037 @default.
- W2029566067 cites W2140194403 @default.
- W2029566067 cites W2140665078 @default.
- W2029566067 cites W2165256606 @default.
- W2029566067 cites W2171161233 @default.
- W2029566067 cites W2305686517 @default.
- W2029566067 cites W2321625540 @default.
- W2029566067 cites W957374447 @default.
- W2029566067 doi "https://doi.org/10.1016/j.mrgentox.2008.09.012" @default.
- W2029566067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18952000" @default.
- W2029566067 hasPublicationYear "2009" @default.
- W2029566067 type Work @default.
- W2029566067 sameAs 2029566067 @default.
- W2029566067 citedByCount "33" @default.
- W2029566067 countsByYear W20295660672012 @default.
- W2029566067 countsByYear W20295660672013 @default.
- W2029566067 countsByYear W20295660672014 @default.
- W2029566067 countsByYear W20295660672015 @default.
- W2029566067 countsByYear W20295660672016 @default.
- W2029566067 countsByYear W20295660672017 @default.
- W2029566067 countsByYear W20295660672018 @default.
- W2029566067 countsByYear W20295660672019 @default.
- W2029566067 countsByYear W20295660672020 @default.
- W2029566067 countsByYear W20295660672022 @default.
- W2029566067 crossrefType "journal-article" @default.
- W2029566067 hasAuthorship W2029566067A5008756451 @default.
- W2029566067 hasAuthorship W2029566067A5031962646 @default.
- W2029566067 hasAuthorship W2029566067A5087086934 @default.
- W2029566067 hasConcept C104317684 @default.
- W2029566067 hasConcept C109316439 @default.
- W2029566067 hasConcept C153911025 @default.
- W2029566067 hasConcept C154317977 @default.
- W2029566067 hasConcept C170493617 @default.
- W2029566067 hasConcept C175656101 @default.
- W2029566067 hasConcept C178790620 @default.
- W2029566067 hasConcept C185592680 @default.
- W2029566067 hasConcept C202751555 @default.
- W2029566067 hasConcept C2777755551 @default.
- W2029566067 hasConcept C2778575167 @default.
- W2029566067 hasConcept C2779071816 @default.
- W2029566067 hasConcept C2780484033 @default.
- W2029566067 hasConcept C30481170 @default.
- W2029566067 hasConcept C54355233 @default.
- W2029566067 hasConcept C544153396 @default.
- W2029566067 hasConcept C544778455 @default.
- W2029566067 hasConcept C55493867 @default.
- W2029566067 hasConcept C66640590 @default.