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- W2029581302 abstract "The final enzyme in the synthesis of methionine from homocysteine in Coprinus lagopus requires a polyglutamate derivative of folic acid. During tests for methionine synthesis from serine and homocysteine by a cell-free homogenate, added tetrahydropteroyl triglutamate was simultaneously degraded by the extract to the unreduced monoglutamate from. Growth of C. lagopus with added methionine alters the endogenous folate pattern, which shows less of the conjugated forms which are necessary for its synthesis. These results suggest a method of regulation of methionine synthesis in this organism, which would supplement the incomplete and possibly quite ineffective end-product control of enzymes involved in the methylation of homocysteine." @default.
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- W2029581302 date "1971-12-21" @default.
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- W2029581302 title "A role for folic acid conjugase in the regulation of methionine synthesis by Coprinus lagopus" @default.
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- W2029581302 doi "https://doi.org/10.1016/0304-4165(71)90166-8" @default.
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