Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029589743> ?p ?o ?g. }
- W2029589743 endingPage "34" @default.
- W2029589743 startingPage "27" @default.
- W2029589743 abstract "Zinc plays a dual role, as an integral part of metabolic machinery and in defense against reactive oxygen species. Hepatocytes are important sites for zinc metabolism for synthesis of zinc metalloproteins and maintaining its homeostasis. However, the factors influencing post absorptive zinc metabolism under normal and oxidative stress (OS) conditions are not well understood. Using rat liver slices, we conducted a series of four in vitro zinc uptake experiments to study influence of ascorbic acid and folic acid in normal and oxidative stress conditions with Zn concentrations representing deficient to excess states (7.7–30.7 millimole/L). Zinc uptakes under OS at these four zinc levels were lower than the normal conditions. Folic acid showed significant inhibitory effect on zinc uptake under both normal and OS conditions in a dose response manner. Nevertheless, dose response of ascorbic acid at four zinc levels indicated its marked enhancing effect under OS condition. Differences in zinc uptake trend lines between the normal and OS conditions for interaction of both the vitamins narrowed down as the zinc levels increased. Our results suggest that folic acid causes inhibitory effect, while ascorbic acid may be protective in OS with reference to zinc uptake." @default.
- W2029589743 created "2016-06-24" @default.
- W2029589743 creator A5030713201 @default.
- W2029589743 creator A5045987226 @default.
- W2029589743 creator A5050117509 @default.
- W2029589743 date "2007-01-01" @default.
- W2029589743 modified "2023-09-27" @default.
- W2029589743 title "Changes in zinc uptake in response to ascorbic acid and folic acid in rat liver slices under normal and oxidative stress conditions" @default.
- W2029589743 cites W1847145347 @default.
- W2029589743 cites W1887679324 @default.
- W2029589743 cites W1970577749 @default.
- W2029589743 cites W1975928583 @default.
- W2029589743 cites W1978468065 @default.
- W2029589743 cites W1992282049 @default.
- W2029589743 cites W1994223795 @default.
- W2029589743 cites W2015331160 @default.
- W2029589743 cites W2031718525 @default.
- W2029589743 cites W2048978309 @default.
- W2029589743 cites W2053108881 @default.
- W2029589743 cites W2053304123 @default.
- W2029589743 cites W2053357610 @default.
- W2029589743 cites W2053504161 @default.
- W2029589743 cites W2058205370 @default.
- W2029589743 cites W2060986363 @default.
- W2029589743 cites W2061298897 @default.
- W2029589743 cites W2063495731 @default.
- W2029589743 cites W2065250371 @default.
- W2029589743 cites W2071858065 @default.
- W2029589743 cites W2085460639 @default.
- W2029589743 cites W2087802628 @default.
- W2029589743 cites W2088777478 @default.
- W2029589743 cites W2103199749 @default.
- W2029589743 cites W2114362297 @default.
- W2029589743 cites W2131046925 @default.
- W2029589743 cites W2134874782 @default.
- W2029589743 cites W2135791659 @default.
- W2029589743 cites W2141874325 @default.
- W2029589743 cites W2144458631 @default.
- W2029589743 cites W2163018505 @default.
- W2029589743 cites W2168653249 @default.
- W2029589743 cites W2187756162 @default.
- W2029589743 cites W329387839 @default.
- W2029589743 doi "https://doi.org/10.1002/biof.5520300104" @default.
- W2029589743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18198399" @default.
- W2029589743 hasPublicationYear "2007" @default.
- W2029589743 type Work @default.
- W2029589743 sameAs 2029589743 @default.
- W2029589743 citedByCount "5" @default.
- W2029589743 countsByYear W20295897432019 @default.
- W2029589743 crossrefType "journal-article" @default.
- W2029589743 hasAuthorship W2029589743A5030713201 @default.
- W2029589743 hasAuthorship W2029589743A5045987226 @default.
- W2029589743 hasAuthorship W2029589743A5050117509 @default.
- W2029589743 hasConcept C126322002 @default.
- W2029589743 hasConcept C134018914 @default.
- W2029589743 hasConcept C178790620 @default.
- W2029589743 hasConcept C185592680 @default.
- W2029589743 hasConcept C2776151105 @default.
- W2029589743 hasConcept C2776928490 @default.
- W2029589743 hasConcept C2986274086 @default.
- W2029589743 hasConcept C31903555 @default.
- W2029589743 hasConcept C535196362 @default.
- W2029589743 hasConcept C55493867 @default.
- W2029589743 hasConcept C62231903 @default.
- W2029589743 hasConcept C71924100 @default.
- W2029589743 hasConcept C86803240 @default.
- W2029589743 hasConceptScore W2029589743C126322002 @default.
- W2029589743 hasConceptScore W2029589743C134018914 @default.
- W2029589743 hasConceptScore W2029589743C178790620 @default.
- W2029589743 hasConceptScore W2029589743C185592680 @default.
- W2029589743 hasConceptScore W2029589743C2776151105 @default.
- W2029589743 hasConceptScore W2029589743C2776928490 @default.
- W2029589743 hasConceptScore W2029589743C2986274086 @default.
- W2029589743 hasConceptScore W2029589743C31903555 @default.
- W2029589743 hasConceptScore W2029589743C535196362 @default.
- W2029589743 hasConceptScore W2029589743C55493867 @default.
- W2029589743 hasConceptScore W2029589743C62231903 @default.
- W2029589743 hasConceptScore W2029589743C71924100 @default.
- W2029589743 hasConceptScore W2029589743C86803240 @default.
- W2029589743 hasIssue "1" @default.
- W2029589743 hasLocation W20295897431 @default.
- W2029589743 hasLocation W20295897432 @default.
- W2029589743 hasOpenAccess W2029589743 @default.
- W2029589743 hasPrimaryLocation W20295897431 @default.
- W2029589743 hasRelatedWork W1578123229 @default.
- W2029589743 hasRelatedWork W1979203789 @default.
- W2029589743 hasRelatedWork W2035358140 @default.
- W2029589743 hasRelatedWork W2041709845 @default.
- W2029589743 hasRelatedWork W2041949500 @default.
- W2029589743 hasRelatedWork W2105661387 @default.
- W2029589743 hasRelatedWork W2126072608 @default.
- W2029589743 hasRelatedWork W2137351911 @default.
- W2029589743 hasRelatedWork W2147256274 @default.
- W2029589743 hasRelatedWork W2163356356 @default.
- W2029589743 hasVolume "30" @default.
- W2029589743 isParatext "false" @default.
- W2029589743 isRetracted "false" @default.
- W2029589743 magId "2029589743" @default.