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• W2029595673 abstract "Lipoic acid is an essential cofactor for a variety of mitochondrial enzymes. We have characterised a gene from Saccharomyces cerevisiae which appears to encode a protein involved in the attachment of lipoic acid groups to the pyruvate dehydrogenase and glycine decarboxylase complexes. The predicted protein product of this gene has significant identity to the lipoyl ligase B of both Escherichia coli and Kluyveromyces lactis. A strain harbouring a null allele of this S. cerevisiae gene is respiratory deficient due to inactive pyruvate dehydrogenase, and is unable to utilise glycine as a sole nitrogen source." @default.
• W2029595673 created "2016-06-24" @default.
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• W2029595673 date "2001-05-01" @default.
• W2029595673 modified "2023-09-29" @default.
• W2029595673 title "The isolation and characterisation of a Saccharomyces cerevisiae gene (LIP2) involved in the attachment of lipoic acid groups to mitochondrial enzymes" @default.
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• W2029595673 doi "https://doi.org/10.1111/j.1574-6968.2001.tb10663.x" @default.
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