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- W2029598055 abstract "PIT1 abnormality is defined as a genetic abnormality in the PIT1 gene, and results in various types of combined deficiencies of thyrotropin (TSH), growth hormone (GH), and prolactin (PRL). We have developed a rapid and nonisotopic procedure for sequencing the human PIT1 gene. The protein coding regions of the PIT1 gene were amplified by PCR, and the products were subjected to sequencing analysis using an autosequencer. With this procedure, we analyzed the PIT1 gene in 17 cases treated with both hGH and thyroid hormone and in one familial case of GH deficiency. No alteration was observed in the protein coding regions of the PIT1 gene of these patients." @default.
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- W2029598055 date "1994-01-01" @default.
- W2029598055 modified "2023-09-23" @default.
- W2029598055 title "Recent Advances in the Diagnosis of <I>PIT1</I> Abnormality" @default.
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- W2029598055 doi "https://doi.org/10.1297/cpe.3.supple4_73" @default.
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