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- W2029603468 abstract "Corneal and limbal epithelial function is highly dependent on its underlying matrix. In this study, we report the in vitro and in vivo effects of a decellularized limbal matrix on corneal and limbal epithelial differentiation and repair. We demonstrate that a limbal matrix helps to maintain epithelial cells in a more proliferative and less differentiated state. We introduce a novel focal injury model to the limbus using an excimer laser and further show that transplanting a decellularized limbal graft after the limbal injury helps to promote epithelialization and reduce corneal haze formation. These results suggest that a decellularized limbal graft may be therapeutically beneficial in clinical cases of focal limbal deficiency." @default.
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- W2029603468 date "2014-02-12" @default.
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- W2029603468 title "<i>In Vivo</i> Evaluation of a Decellularized Limbal Graft for Limbal Reconstruction" @default.
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- W2029603468 doi "https://doi.org/10.1155/2014/754245" @default.
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