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- W2029626869 abstract "Craniopharyngiomas are embryogenic malformations of the sellar region. With an overall incidence of 0.5-2.0 new cases per million population per year, approximately 30-50% of all cases represent childhood craniopharyngioma. Therapy of choice in patients with favorable tumor localization is complete resection with a specific focus on maintaining functions of the optical nerve and hypothalamic-pituitary axes. In patients whose unfavorable tumor localization makes maintaining hypothalamic functionality surgically challenging, a limited resection followed by local irradiation is recommended. The overall survival rates are high (92%) but relapses and reduced QoL in survivors are also frequent. Because irradiation is efficient in preventing tumor progression, appropriate timing of post-surgical irradiation is currently under investigation in a randomized trial (KRANIOPHARYNGEOM 2007). Childhood craniopharyngioma should be recognized as a chronic disease requiring constant monitoring of the clinical and QoL consequences in order to provide optimal care of surviving patients." @default.
- W2029626869 created "2016-06-24" @default.
- W2029626869 creator A5020481478 @default.
- W2029626869 date "2014-01-13" @default.
- W2029626869 modified "2023-10-14" @default.
- W2029626869 title "Childhood craniopharyngioma: treatment strategies and outcomes" @default.
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- W2029626869 doi "https://doi.org/10.1586/14737175.2014.875470" @default.
- W2029626869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24428758" @default.
- W2029626869 hasPublicationYear "2014" @default.
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