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- W2029654829 abstract "Further investigation of the effect of bound testosterone on the susceptibility of human serum albumin to tryptic hydrolysis has revealed a stimulation of hydrolysis at low binding levels, becoming an inhibition at higher binding levels. The inhibition, but not the stimulation, is associated with a two-stage steroid-induced proton release phenomenon which may involve the cysteine (SH) group and tyrosine residues. Proton release is also induced by Ca2+ and ethanol. The nature of the effect and the influence of Ca2+ suggests that stimulation of hydrolysis is associated with the presence of one molecule of testosterone and inhibition with the presence of 2–5 molecules at a set of sites which are thermodynamically equivalent." @default.
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- W2029654829 date "1978-10-01" @default.
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- W2029654829 title "Testosterone-induced proton release and inhibition of tryptic hydrolysis of albumin" @default.
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- W2029654829 doi "https://doi.org/10.1016/0304-4165(78)90054-5" @default.
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