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• W2029666944 abstract "Guided tissue barriers using materials such as collagen are used in the hope of excluding epithelium and the gingival corium from the root surface or alveolar bone to facilitate regeneration. Convention suggests that the longer a membrane remains intact, the better the regeneration results. The purpose of this study was to determine the resorption rates of various collagen membranes in the oral cavity of dogs. Twelve adult mongrel dogs had three different collagen membranes (BioGide, AlloDerm porcine-derived, and AlloDerm human-derived) randomly inserted and secured into surgical pouches made in their palates. Full-thickness tissue punch biopsy specimens taken at 1, 2, 3, or 4 months after surgery were evaluated histologically for membrane intactness and other associated changes. At 1 month, all membranes had slight to moderate degradation. At 2 months, all membranes had moderate to severe degradation with the exception of one AlloDerm human-derived membrane that was intact. At 3 months, all membranes had severe degradation to not identifiable. At 4 months, all membranes had severe degradation to completely absent. Blood vessel penetration varied from none to moderate. Inflammation was found in only two samples. In the dog, all three tested collagen membranes showed slight to moderate degradation at 1 month and were severely degraded to completely absent at 4 months. Within the limits of transferring animal data to humans, clinicians need to be aware of these resorption rates when selecting membranes for guided tissue and bone regeneration." @default.
• W2029666944 created "2016-06-24" @default.
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• W2029666944 date "2001-03-01" @default.
• W2029666944 modified "2023-09-26" @default.
• W2029666944 title "Collagen Membrane Resorption in Dogs: A Comparative Study" @default.
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• W2029666944 doi "https://doi.org/10.1097/00008505-200101000-00016" @default.
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